Hemodialysis patients are prone to high stress and anxiety levels related to the acute coronavirus epidemic. Aim: To evaluate the effect of web-based education on quality of life and anxiety level among patients undergoing hemodialysis during Covid-19 lockdown. Methods: Subjects and method: Design: Quasi-experimental research design pre-post-test was utilized to achieve the aim of this study. Settings: The study was conducted at Port Said City in Egypt. Sample: Purposive samples of 300 patients undergoing hemodialysis were enrolled in this study during the period of the beginning of june 2020 to end of October 2020. Four tools were used in data collection: (I): A self-administered questionnaire (pre and post-test format) was used to assess the patient's demographic characteristics, medical history, and patient's knowledge about hemodialysis (pre and post-test format); (II): Corona Disease Anxiety Scale (CDAS); (III): Quality of Life (QoL) scale, and (IV) Patient's satisfaction regarding web-based education. Results: The present study revealed that there were highly statistically significant differences between patients' knowledge and their anxiety during COVID-19 pandemic outbreaks pre and post-implementation of the web-based education. Also, Significant improvements in the QoL (p<0.001) were revealed after the implementation of web-based education. Conclusion: the study concluded that web-based education achieved significant improvements in the patient's knowledge and has a positive effect on improving their quality of life and minimizing anxiety levels during the covid-19 lockdown. Recommendations: The Web Based education could be applied and carefully planned for all patients undergoing hemodialysis as a new teaching method for proving health issues. Provision of continuing follow-up education programs are recommended for patients undergoing hemodialysis
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