KF-Melamine formaldehyde resin (KF-MFR) was demonstrated to be a highly efficient heterogenious catalyst for cross-aldol condensation under microwave irradiation. In this synthesis, various aldehydes and ketones were condensed together in the presence of supported KF on melamine-formaldehyde resin to afford different chalcone derivatives in good to excellent yields. KF-MFR proved to have unique termal and chemical resistance and can be reused for many consecutive runs without remarkable loss in catalytic activity.
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