'The Tree of Life' or 'Miracle Tree' is the name of the plant of Moringa oleifera (Shajna). Moringa oleifera is one of the important plants in plant kingdom. Its leaves and fruits are used as vegetable in Indian sub continent, at the same time each part of the plant rich with some important medicinal values. It is now considered as a valuable source of several unique products for the medicines against various diseases. The present review is to focus on the nutritive values, physico-chemical properties, phyto-chemicals and pharmacological activities of M. oleifera. Various parts of the plant like seeds, leaves, flowers, bark and fruits have been investigated for their significant pharmacological activity. Phyto-chemicals like flavanoid, anthraquinone, alkaloids, essential oils, tannic acid, carotene, glucose have been reported for significant antioxidant, hepatoprotective, anticancer, aphrodisiac, antiinflammatory, antihyperlipidaemic, antihyperglycaemic and antiulcer activities of Drumstick tree and emphasizes the need for further exploring available information.
Insulin is a lifesaving hormone which is secreted from beta cell of Pancreas. It helps to reduce high blood sugar in the blood by trapping the glucose molecule and enter into cell. Now a day, insulin resistance diabetes mellitus (IRDM) becomes a serious public health problem in the world and also a great headache to the scientific communities. That’s why, world scientist are enormously seeking the alternative of insulin or insulin like effective drugs. It has been proved that nature is having all remedies to combat disease related morbidity and mortality. We have to search, we have to know, we have to identify and we have to apply appropriate technology to evaluate new molecules, new metabolites or active compounds for reducing the devastating effects of diabetes as well as insulin resistance diabetes mellitus. Evidence based studies showed that berbery, bitter melon, cinnamon tree, gardenia, korean pine, little dragon, mango, pygeum, fenugreek and lychee composed of incretins mimetic compounds. But isolation of active metabolomics and the multicentre base clinical trials are needed to propagate the herbal medicine in the world. It is an attempt to amalgamate, to congregate, to concise some incretins mimetic medicinal plants which will help to get new generic compound and also give new clue for further research on DM.
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