The present study results link the systemic effects of induced periodontitis with changes in hepatic tissues such as microvesicular steatosis, likely caused by an increase in oxidative stress and lipid peroxidation. The findings from the present study implicate an association between a decrease of pericytes and liver disease caused by ligature-induced periodontitis in rats.
Objective. The aim of this systematic review was to investigate the advances in the study of medicinal plants and their biologic effects on periodontitis in animal models. Study Design. A systematic search was conducted by three independent researchers, who screened articles published up to March/2016, to identify the studies that contained sufficient and clear information on the association of the medicinal plants and periodontitis in murine models. The searches were performed using PubMed, Cochrane, and Science Direct databases. Results. After a critical analysis of titles and abstracts, 30 studies were finally eligible for analysis. The studies presented a great diversity of the experiment designed regarding the methods of induced periodontitis and the evaluation of the medicinal plants efficacy. None of the studies described the possible toxic effects associated with the administration of the plant material to animals and whether they could prevent damage to organs caused by systemic effect of induced periodontitis. Gel-based formulations containing plant substances are seen as an interesting strategy to treat periodontitis. Conclusions. In this systematic review, the state-of-the-art knowledge on the medicinal plants and the induced periodontitis was critically evaluated and discussed from the experiment designed to the possible clinical application.
Ectodermal dysplasia (ED) is a genetically heterogeneous condition resulting from clinical anomalies of structures derived from the ectoderm, such as the hair, nails, sweat glands, and teeth. This clinical report presents the case of a child diagnosed with hypohidrotic ED at 2 years of age; clinical and imaging evaluation was performed with 6-year follow-up, and we present details of the prosthetic dental care, with a 12-month follow-up. The patient's masticatory capacity had improved, leading to the child gaining 4 kg. In conclusion, prosthetic management was noninvasive and appeared to lead to developmental benefits for the patient.
Paradental cyst is an inflammatory odontogenic cyst in the mandibular area, with a rare occurrence of 0.9-4.7% among odontogenic cysts, developing laterally with the cementoenamel junction of a totally or partially erupted molar. [1,2] It was first described by Main in 1970  and Craig suggested the name paradental cyst.  The World Health Organization (WHO) has defined the paradental cyst as a cyst occurring near to the cervical margin of the lateral aspect of a root as a consequence of an inflammatory process in a periodontal pocket. A distinctive form of the paradental cyst arises on the buccal and distal aspects of erupted mandibular molars where there is a history of pericoronitis.  Patients report different degrees of pain, tenderness, and swelling and, in some cases, it can be observed along with suppuration through the periodontal pocket. [2,6] Radiographically, the paradental cyst can have different features depending on the superposition of anatomical structures, presence of infection, and size and location of lesion,  however, is often presented as a well-defined A B S T R A C T Paradental cyst is an inflammatory odontogenic cyst linked with mandibular molars. The occurrence rate of the lesion ranges from 0.9 to 4.7% suggesting its infrequency. The histopathologic findings in hematoxylin and eosin routine staining are not pathognomonic, and the correlation with clinical and imaging characteristics is essential to establish the final diagnosis. The periapical radiographs show a unilocular radiolucency on the distal or disto/buccal aspect of the involved tooth, however, the lesion can superimpose over the roots and mimic periapical pathology. We report the imaging features of a rare bilateral paradental cyst with an emphasis on magnetic resonance imaging and cone beam computed tomography to help a correct identification and characterization of the cyst and to reliably establish the diagnosis.
<p>Magnetic resonance imaging (MRI) is a type of imaging study considered the gold standard in the analysis of the internal structure and content of intraosseous lesions, allowing for their inherent characteristics of acquisition, determine the nature and differential diagnosis between changes that have aspects Similar to other imaging modalities, such as on radiographs and computed tomography (CT) and also has the great advantage of not being an invasive method, since it does not use ionizing radiation.The ultrasound (U.S.) and MRI provides images without showing deleterious effects to living organisms, enabling the differentiation between solid and cystic lesions, however, lacks the ability of MRI to provide an anatomical detailing determined, nor information about the chemical composition of the lesions, which would be crucial in determining the diagnosis of the same. The dentigerous cyst is among the most frequent odontogenic lesions that affect the maxillomandibular complex, requiring a thorough assessment of its extent and proximity to anatomical structures as well as the differential diagnosis with other lesions. This study aimed to emphasize the use of MRI and U.S. in the diagnosis of lesions dentomaxilofaciais, describing a clinical case of dentigerous cyst in these imaging modalities were used as complementary tests.<strong></strong></p>
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