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The present study investigated the effect of transplanting endothelial progenitor cells (EPCs) transfected with the vascular endothelial growth factor gene (VEGF165) into the corpora cavernosa of rats with diabetic erectile dysfunction (ED). A rat model of diabetic ED was constructed via intraperitoneal injection of streptozotocin. After streptozotocin treatment, pre-treated EPCs from each of three groups of rats were transplanted into their corpora cavernosa. Our results, following intracavernosal pressure (ICP) monitoring, showed that ICP increased significantly among rats in the trial group when compared to the results from rats in the blank-plasmid and control groups during basal conditions and electrical stimulation (P<0.01 for both comparisons). Histological examination revealed extensive neovascularisation in the corpora cavernosa of rats in the trial group. Fluorescence microscopy indicated that many of the transplanted EPCs in the trial group survived, differentiated into endothelial cells and integrated into the sites of neovascularisation. Based on the results of this study, we conclude that transplantation of VEGF165-transfected EPCs into the corpora cavernosa of rats with diabetic ED restores erectile function.

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With the aim of finding a low-cost, safe, and reliable way to reduce costs of space launch, a maglev launch assist vehicle (Maglifter) is proposed. We present a permanent magnet–high temperature superconductor (PM-HTS) interaction maglev system for the Maglifter, which consists of a cryostat with multi-block YBaCuO bulks and a flux-collecting PM guideway. We obtain an optimum bulk arrangement by measuring and analysing the typical locations of HTSs above the PM guideway. We also measure the levitation abilities of the arrangement at different field cooled heights (FCHs) and different measuring distances (MDs), and find that the lower FCH and the lower MD both cause more magnetic flux to penetrate the HTSs, and then cause stronger lateral stability. A demonstration PM-HTS maglev test vehicle is built with four maglev units and two PM guideways with the length of 7 m. Its levitation characteristics in different FC and loading conditions are demonstrated. By analysing the maglev launch assist process, we assess that the low FC is useful for increasing the lateral stability of the Maglifter.