BackgroundHelicobacter pylori is one of the most controversial bacteria in the world causing diverse gastrointestinal diseases. The transmission way of this bacterium still remains unknown. The possibility of zoonotic transmission of H. pylori has been suggested, but is not proven in nonprimate reservoirs. In the current survey, we investigate the presence of H. pylori in cow, sheep and goat stomach, determine the bacterium virulence factors and finally compare the human H. pylori virulence factors and animals in order to examine whether H. pylori might be transmitted from these animals to human beings.MethodsThis cross- sectional study was performed on 800 gastric biopsy specimens of cows, sheep, goats and human beings. The PCR assays was performed to detection of H. pylori, vacA and cagA genes. The PCR products of Ruminant’s samples with positive H. pylori were subjected to DNA sequencing analysis. Statistical tests were applied for data analysis.ResultsOverall 6 (3%) cows, 32 (16%) sheep and 164 (82%) human beings specimens were confirmed to be H. pylori positive; however we were not able to detect this bacterium in all 200 goat samples. The vacA s1a/m1a was the predominant H. pylori genotype in all three kinds of studied population. There was 3.4–8.4% variability and 92.9-98.5% homology between sheep and human samples.ConclusionsConsidering the high sequence homology among DNA of H. pylori isolated from sheep and human, our data suggest that sheep may act as a reservoir for H. pylori and in the some extent share the ancestral host for the bacteria with human.
Background Anterior cruciate ligament trauma is one of the most common knee injuries in professional athletes. This study aimed to investigate the effects of kinesio taping on kinesiophobia, balance, and functional performance in athletes after anterior cruciate ligament reconstruction. Methods This randomized, placebo-controlled clinical trial was performed on 20 athletes with anterior cruciate ligament reconstruction (mean age 32.3 ± 6.2 years) at the time of return to sport. The subjects were randomly assigned to the kinesio tape (KT) group (n = 10) or placebo KT group (n = 10). While subjects under taped, the following outcomes were measured at baseline, 10 minutes after the intervention, and 2 days later. Kinesiophobia, balance, strength, and functional / agility performance were assessed by the Tampa Scale, Y balance test (YBT), single-leg hops, and 10-yard extremity functional test, respectively. Results The results did not show a significant difference between-group post-intervention differences in kinesiophobia (Mean between-group difference = − 6.30, 95% CI = − 4.35 to 1.42, P-value = 0.17). Likewise, no significant statistical difference was observed between two study groups in terms of YBT scores (Mean between-group difference ranged over = − 6.30, 95% CI = − 1.1 to 4.7, the effect sizes ranged over = 0.01 to 0.31), P-value > 0.05), Single Leg Hop (Mean between-group difference = − 0.48, 95% CI for difference ranged over = − 10.3 to 9.3, effect size = 0.001, P-value = 0.918), and 10 Yard test scores (Mean between-group difference = − 0.30, 95% CI = (− 1.3 to 0.75), effect size = 0.02, P-value = 0.55) at 2 days after the KT. In the KT and placebo KT groups, RMANOVA indicated that the differences in all variables scores were significant over time with large effect sizes (effect size ranged over = 0.94–0.99; all P-value < 0.001). Conclusion This study gives no support for any beneficial effect of kinesio taping on the reduction of kinesiophobi or improvement of balance score and functional performance in athletes with post anterior cruciate ligament reconstruction. Trial registration This study was registered in the Iranian Clinical Trial Center with the code IRCT20190130042556N1, registered 12 February 2019.
Background: Vibration as one of the harmful physical factors is relatively present in a wide range of jobs. Musculoskeletal disorders (MSDs) are among the most prevailing complaints of workers encountering occupational factors for example vibration. Therefore, this study was conducted to investigate vibration and its association with the MSDs in upper limbs of heavy mine vehicles drivers. Materials and Methods: This cross-sectional study was conducted, on heavy mine vehicles of Gol-Gohar Sirjan Centre, Sirjan, Iran. In general, 288 drivers with 92 vehicles were working at the mine site. SVAN958 vibration meters and the Nordic Musculoskeletal Questionnaire were used to measure whole body vibration and upper limb MSDs, respectively. Finally, the data were analysed using SPSS. Results: The highest average equilibrated acceleration was in graders (2.179 m/s 2) and drills had the lowest average acceleration (0.479 m/s 2). Prevalence of MSDs within past 12 months showed a significant difference in the neck (P = 0.044) and elbow (P = 0.023) between case and control group. The whole body vibration variable was associated with MSDs in the neck (P = 0.020) and wrist/hands (P = 0.030), and with increase in vibration the MSDs showed a 59% increase in neck and 72% in wrist/hands. In multivariate analysis, the whole body vibration variable had a significant relation with MSDs in wrist/hand (P = 0.027) and caused an 83% increase in the risk of MSDs per each unit in wrist/hand. Conclusions: The prevalence of disorders in studies with short duration is probably not quite visible; however, by increasing the working experience with these vehicles which have higher vibration than standard rates, the chance of developing MSDs increases.
Studies collectively imply that the reciprocal link has no effect on walking when using reciprocating gait orthoses (RGOs). There may be differences between the 2 configurations of the RGO (eg, isocentric reciprocating gait orthosis [IRGO] and IRGO without reciprocating link), but the specific benefits and problems encountered in their use must be understood. To highlight more evidence for the mechanical function of the reciprocal link in RGOs used for walking by individuals with spinal cord injury (SCI). Nine people with SCI participated in this study. Gait analysis was performed in 2 conditions (walking with IRGO and walking with IRGO without reciprocating link) in a random order. The Vicon digital capture system was used to obtain kinematic data. There were significant differences between each orthotic configuration in terms of speed of walking ( = .029), step length ( = .048), hip joint range of motion (ROM) ( ≤ .001), and lateral and vertical compensatory motions ( ≤ .001). There was no significant difference between each orthotic configuration in cadence ( = .162). The reciprocating link in IRGO improved the walking parameters in SCI patients.
Background Musculoskeletal disorders (MSDs) of the upper extremities and computer use are common in modern societies, and both show a growing trend. This study was conducted to determine the posture and 3D moments of wrist and elbow joints at different keyboard distances on a desk. Methods Twelve healthy right-handed male volunteers attended the motion analysis laboratory. A keyboard was placed at three different distances from the participants' bodies while performing a standard computer task. The workstation was adjusted according to ANSI/HFES-100-2007 standard for each participant to maintain comfortable ergonomic posture for controlling confounding variables. Qualisys motion capture system, OpenSim software (Ver. 4.1), and visual analog scale (VAS) were used to collect and analyze the data. Also, SPSS (Ver.16) was used to descriptive, Friedman and Wilcoxon tests. Results The highest levels of wrist flexion and radial deviation as well as elbow flexion and pronation were observed when the keyboard was at the edge of the desk. When the keyboard was 8 cm away from the edge of the desk, the wrist flexion, deviation, and pronation had the least values. With increasing the distance of the keyboard from the edge of the desk, the range of motion (ROM) of the wrist flexion and deviation as well as elbow flexion, supination and pronation decreased. The joint moments were not significantly different for the different studied keyboard positions (P-value > 0.05). Conclusions However, a cut-off point has to be specified because large keyboard distances cause high extension and flexion of the limbs. The position of the keyboard relative to the body is an important parameter in computer work and has a significant impact on the posture of the upper extremities. A keyboard should be located at a distance that allows the upper extremities to remain in a neutral position so that the risk of MSDs is reduced.
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