Introduction and purpose: The purpose of this study is to review literature about alterations to treatment regimens to lung cancer during COVID-19 pandemic accessible on PubMed platform. In pulmonary neoplasms, early diagnosis and treatment is a key to ensure patient safety. Burdening of healthcare systems during pandemic has resulted in many obstacles in oncologic treatment. A brief description of the state of knowledge: The lung cancer is the most frequent and the most deadly cancer in men and women. COVID-19 is a pulmonary infectious disease whose spread around the world has resulted in a pandemic. At the onset of the worldwide pandemic, many institutions, including healthcare facilities were closed, making it more difficult to provide oncological patients the treatment compliant with the standards. The anxiety of patients caused by the pandemic has caused delays in treatment that can cause progression of the disease. In patients with lung cancer mortality of COVID-19 was around 50%, which made their visits at hospital hazardous. Before the accessibility of anti-COVID-19 vaccines telemedical healthcare was one of the ways to provide healthcare to oncological patients. Conclusions: Patients with lung cancer are one of the risk groups of COVID-19. Delays in their treatment caused by the pandemic are potentially dangerous and negatively affect the therapy. Telemedicine is a useful too provide medical care, but has its own limitations.
Introduction: Depression is a mental disorder that is increasingly being diagnosed in middle and more developed countries (MDC). Symptoms of depression in patients with severe depressive disorder (MDD) include sadness, regret, negative thoughts, anxiety, and more.The aim of the study: The aim of the study was to summarize the latest research (from 2020) on factors related to the occurrence of depression, as well as the current findings on depression (also those related to the COVID-19 pandemic).Material and method: For this purpose, scientific search engines such as PubMed and Google Scholar were used.Description of the state of knowledge: In 2020, apart from research on pathomechanisms and environmental factors, a large part of the research focused on the COVID-19 pandemic as a risk factor for the development of depression symptoms. Many studies from different parts of the world have confirmed that a pandemic can have a significant impact on the occurrence of depression. Summary: There are many factors that can cause depression and it is important to keep them in mind both in everyday life and in clinical practice. Studies from various parts of the world have shown that the COVID-19 pandemic has exacerbated the experience of depressive symptoms, also in those who have not yet been diagnosed with MDD. The degree of severity of depressive symptoms depended on such factors as: financial situation, social isolation.
Introduction and purpose: Gastric cancer (GC) is one of the most frequent malignancies around the world. There were nearly 1 million new cases in 2018. Gastric malignancies have heterogeneous etiopathogenesis. Lifestyle, socioeconomic status, blood group A, medical condition, Helicobacter Pylori infection, family history, genetic polymorphism, diet, demographic characteristics, occupational exposure, ionizing radiation are considered as predisposing factors.Objective: The purpose of our study is to review a currently available data on PubMed about risk factors of gastric cancer to consider better understanding of gastric cancer etiology.A brief description of the state of knowledge: Current studies suggest that red meat, pickled vegetable or alcohol consumption, low socioeconomic status, cigarette smoking, blood group A and Helicobacter Pylori infection increase risk of GC. Decreased risk of gastric cancer is observed in case of white meat consumption, statin and non-steroidal anti-inflammatory drugs intake. It seems that family history and other genetic predispositions may have a crucial role in gastric cancer development.Conclusions: Variety of environmental, genetic and medical factors are considered with an increased risk of gastric cancer. The awareness of its existence facilitates pathogenesis of gastric malignancies and enables the implementation of proper diagnostic procedures, screening programs and prophylaxis.
Background: Lung cancer is the second most common and fatal cancer worldwide. The first-line treatment for early-stage primary lung cancer is surgical resection, but surgery is contraindicated in 60% of cases. Alternatives then include local treatments such as radiofrequency ablation (RFA), microwave ablation (MWA) and cryoablation. With the current scientific knowledge of these treatments, the fundamental question of their therapeutic efficacy must be answered. Aim and methods: To present recent scientific findings on the efficacy of the three main methods of thermoablation for lung cancer. A systematic review of scientific papers on the indicated topics from the last 5 years was performed. Several dozen publications were selected for the purpose of this study. Results: As shown in the studies, the therapeutic effect of MWA controls tumour progression with few side effects and high safety, especially in patients with tumours <3.5 cm in diameter. Cryotherapy, on the other hand, not only improves quality of life, but can also prolong patients' survival. The relatively low risk of this procedure goes hand in hand with its minimal invasiveness, leading to a low complication rate. RFA, on the other hand, shows no greater treatment efficacy than surgical resection, stereotactic radiotherapy. Conclusions: MWA and cryoablation techniques are interesting alternatives to surgical resection for non-small cell lung cancer, improving the quality of life of patients regardless of the stage of their disease. The question of increasing the availability of this type of treatment in the health care system therefore remains crucial.
Summary Introduction and purpose: The purpose od this study is to describe changes in epidemiological trends of fractures, especially osteoporotic fractures, during COVID-19 pandemic. Before the pandemic, fractures in the young population were more frequent than in elderly population, because of more active lifestyle. A brief description of the state of knowledge: COVID-19 pandemic and lockdown has effectively reduced people’s mobility and ability to travel. This has resulted in lowered rate of traumatogenic incidents that cause fractures, including traffic accidents and accidents during performing sport. When people spend more time at their homes, incidence of household fractures is growing, especially in elderly population. Osteoporosis makes bones of elderly people more suspectible to fracture. Majority of drugs used in treatmen for osteoporosis are said not to interact with risk or severity of COVID-19 infection. Conclusions: During the COVID-19 pandemic, geriatric fractures have become one of the severe problems for healthcare systems. Isolation at people’s homes has resulted in increased rate of fractures occuring at home, especially in elderly population. Difficulties caused by pandemic made rates of properly performed osteoporotic treatment lower, increasing risk of fractures even more. Mortality after fractures has risen even in patients with negative result of testing for COVID-19.
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