A sensor system for measurement of pressure and shear at the lower limb residuum/socket interface is described. The system comprises of a flexible sensor unit and a data acquisition unit with wireless data transmission capability. Static and dynamic performance of the sensor system was characterised using a mechanical test machine. The static calibration results suggest that the developed sensor system presents high linearity (linearity error ≤3.8%) and resolution (0.9kpa for pressure and 0.2kpa for shear). Dynamic characterisation of the sensor system shows hysteresis error of approximately 15% for pressure and 8% for shear. Subsequently, a pilot amputee walking test was conducted. Three sensors were placed at the residuum/socket interface of a knee disarticulation amputee and simultaneous measurements were obtained during pilot amputee walking test. The pressure and shear peak values as well as their temporal profiles are presented and discussed. * Corresponding Author: Piotr Laszczak, Engineering Materials Research Group, Faculty of Engineering and the Environment, University of Southampton, SO17 1BJ, Southampton, UK; Email, P.Laszczak@soton.ac.uk; Phone, 07513362435 Preprint submitted to Medical Engineering and PhysicsMarch 1, 2016In particular, peak pressure and shear of approximately 58kPa and 27kPa, respectively, were recorded. Their temporal profiles also provide dynamic coupling information at this critical residuum/socket interface. These preliminary amputee test results suggest strong potential of the developed sensor system for exploitation as an assistive technology to facilitate socket design, socket fit and effective monitoring of lower limb residuum health.Abstract word count: 200

The bespoke interface between a lower limb residuum and a prosthetic socket is critical for an amputee's comfort and overall rehabilitation outcomes. Analysis of interface kinematics and kinetics is important to gain full understanding of the interface biomechanics, which could aid clinical socket fit, rehabilitation and amputee care. This pilot study aims to investigate the dynamic correlation between kinematic movement and kinetic stresses at the interface during walking tests on different terrains. One male, knee disarticulation amputee participated in the study. He was asked to walk on both a level surface and a 5° ramped surface. The movement between the residuum and the socket was evaluated by the angular and axial couplings, based on the outputs from a 3D motion capture system. The corresponding kinetic stresses at anterior-proximal (AP), posterior-proximal (PP) and anterior-distal (AD) locations of the residuum were measured, using individual stress sensors. Approximately 8° of angular coupling and up to 32 mm of axial coupling were measured when walking on different terrains. The direction of the angular coupling shows strong correlation with the pressure difference between the PP and AP sensors. Higher pressure was obtained at the PP location than the AP location during stance phase, associated with the direction of the angular coupling. A strong correlation between axial coupling length, L, and longitudinal shear was also evident at the PP and AD locations i.e. the shortening of L corresponds to the increase of shear in the proximal direction. Although different terrains did not affect these correlations in principle, interface kinematic and kinetic values suggested that gait changes can induce modifications to the interface biomechanics. It is envisaged that the reported techniques could be potentially used to provide combined kinematics and kinetics for the understanding of biomechanics at the residuum/socket interface, which may play an important role in the clinical assessment of prosthetic component settings, including socket fit quality.

Introduction Trans-femoral amputees are at risk of musculoskeletal problems that are in part caused by loading asymmetry during activities, such as prolonged standing, particularly on uneven or sloped ground. Methods Four prosthetic conditions were tested; microprocessor knee ‘standing support’ mode activated (ON) and deactivated (OFF), combined with a rigidly attached foot (RA) and with an articulating, hydraulic ankle-foot (HA). Five trans-femoral amputees and five able-bodied controls were measured using a motion capture system and a force plate while standing, facing down a 5° slope. Ground reaction force distributions and centre-of-pressure root-mean-square (COP RMS) were calculated as outcome measures. Results Compensatory kinematic adjustments were observed for RA conditions but not for HA conditions. HA-OFF reduced ground reaction force degree-of-asymmetry for all five amputees, compared to RA-OFF. RA-ON reduced ground reaction force degree-of-asymmetry for four amputees, compared to RA-OFF. In terms of balance, the HA conditions reduced the mean inter-limb COP RMS by 24–25% compared to equivalent RA conditions, while ON conditions reduced it by 9–11%, compared to equivalent OFF conditions. Conclusions It is important to consider both prosthetic knee and ankle technologies when prescribing devices to trans-femoral amputees. The combination of hydraulic ankle and knee standing support technologies produced outcomes closest to normal biomechanics.

Clinical Research Abstracts British Equine Veterinary Association Congress 2015 Foreword and AcknowledgementsThis supplement is devoted to the publication of abstracts from the 2015 Congress of The British Equine Veterinary Association. The quality of research at the Congress was, as in previous years, high, and the selection process was difficult. Despite the inclusion of a larger number of research communications than in previous years only two-thirds of those submitted could be accepted. This year's Congress committee utilised the selection process initiated last year by Professor Celia Marr in partnership with EVJ. Abstracts were reviewed and objectively graded by two peer reviewers and a member of the Congress Committee before being subjected to a final selection process overseen by the Congress Chair. Thereafter, abstracts had to satisfy the requirements of EVJ for publication in this supplement. Those authors who have had their work accepted should be proud of their achievement. Those who were unsuccessful are doubtless disappointed; however, they have the reassurance that the standard was high and the process was fair.Implementing such a process necessitates a considerable amount of work by dozens of individuals. I am extremely grateful to Professor Celia Marr, Sue Wright and Jane Woodley at EVJ for inviting the Congress Committee to work in partnership with them and for enabling us to utilise their review process. Without the infrastructure provided by EVJ, such a comprehensive review process would not have been possible, and without the endless patience and assistance of the aforementioned individuals, it could not have worked. The Congress Committee themselves: Debbie Archer, Madeleine Campbell, Huw Griffiths, Philip Ivens, Andy Fiske-Jackson, Malcolm Morley, Michael Schramme, Henry Tremaine and Lesley Young deserve thanks and recognition for a year of hard work. Particular thanks also to all of the anonymous peer reviewers who receive no recognition but gave their time not only to grade the abstracts submitted but also to provide constructive feedback to their authors.The selection process adopted for BEVA Congress sets a standard for other meetings to follow. Given the increasing competition for acceptance of research communications at major international meetings, and the importance of achieving acceptance for those seeking to fulfil the requirements of specialist colleges, such a rigourous selection process seems only right. David Rendle Chairman BEVA 2015 Scientific Programme Guardians Congress Session Sponsors EFFICACY OF OVIDUCTAL FLUSHING WITH PGE2, IN MARES, IN AND OUT OF THE BREEDING SEASONMartynski, P.D., Payne, R.J. and Wylie, C.E. Rossdales Equine Hospital & Diagnostic Centre, Cotton End Road, Exning, Newmarket, Suffolk, CB8 7NN, UK. Email: pmartynski@rvc.ac.uk Reasons for performing study: There are limited data surrounding the efficacy of oviductal flushing in restoring fertility in mares with repeated returns to oestrus. Objectives:To determine the conception and foaling rates in...

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Mechanical coupling at the interface between lower limb residua and prosthetic sockets plays an important role in assessing socket fitting and tissue health. However, most research lab-based lower limb prosthetic simulators to-date have implemented a rigid socket coupling. This study describes the fabrication and implementation of a lower limb residuum/ socket interface simulator, designed to reproduce the forces and moments present during the key loading phases of amputee walking. An artificial residuum made with model bones encased in silicone was used, mimicking the compliant mechanical loading of a real residuum/socket interface. A 6-degree-of-freedom load cell measured the overall kinetics, having previously been incorporated into an amputee's prosthesis to collect reference data. The developed simulator was compared to a setup where a rigid pylon replaced the artificial residuum. A maximum uniaxial load of 850 N was applied, comparable to the peak vertical ground reaction force component during amputee walking. Load cell outputs from both pylon and residuum setups were compared. During weight acceptance, when including the artificial residuum, compression decreased by 10%, while during push off, sagittal bending and anterior-posterior shear showed a 25% increase and 34% decrease, respectively. Such notable difference by including a compliant residuum further highlighted the need for such an interface simulator. Subsequently, the simulator was adjusted to produce key load cell outputs briefly aligning with those from amputee walking. Force sensing resistors were deployed at load bearing anatomic locations on the residuum/socket interface to measure pressures and were compared to those cited in the literature for similar locations. The development of such a novel simulator provides an objective adjunct, using commonly available mechanical test machines. It could potentially be used to provide further insight into socket design, fit and the complex load transfer mechanics at the residuum/socket interface, as well as to evaluate the structural performance of prostheses.

Simple 2D models of walking often approximate the human body to multi-link dynamic systems, where body segments are represented by rigid links connected by frictionless hinge joints. Performing forward dynamics on the equations of motion (EOM) of these systems can be used to simulate their movement. However, deriving these equations can be time consuming. Using Lagrangian mechanics, a generalised formulation for the EOM of n-link open-loop chains is derived. This can be used for single support walking models. This has an advantage over Newton-Euler mechanics in that it is independent of coordinate system and prior knowledge of the ground reaction force (GRF) is not required. Alternative strategies, such as optimisation algorithms, can be used to estimate joint activation and simulate motion. The application of Lagrange multipliers, to enforce motion constraints, is used to adapt this general formulation for application to closed-loop chains. This can be used for double support walking models. Finally, inverse dynamics are used to calculate the GRF for these general n-link chains. The necessary constraint forces to maintain a closed-loop chain, calculated from the Lagrange multipliers, are one solution to the indeterminate problem of GRF distribution in double support models. An example of this method's application is given, whereby an optimiser estimates the joint moments by tracking kinematic data.

-An investigation into the kinematic and kinetic predictions of two "inverted pendulum" (IP) models of gait was undertaken. The first model consisted of a single leg, with anthropometrically correct mass and moment of inertia, and a point mass at the hip representing the rest of the body. A second model incorporating the physiological extension of a head-arms-trunk (HAT) segment, held upright by an actuated hip moment, was developed for comparison. Simulations were performed, using both models, and quantitatively compared with empirical gait data. There was little difference between the two models' predictions of kinematics and ground reaction force (GRF). The models agreed well with empirical data through mid-stance (20-40% of the gait cycle) suggesting that IP models adequately simulate this phase (mean error less than one standard deviation). IP models are not cyclic, however, and cannot adequately simulate double support and stepto-step transition. This is because the forces under both legs augment each other during double support to increase the vertical GRF. The incorporation of an actuated hip joint was the most novel change and added a new dimension to the classic IP model. The hip moment curve produced was similar to those measured during experimental walking trials. As a result, it was interpreted that the primary role of the hip musculature in stance is to keep the HAT upright. Careful consideration of the differences between the models throws light on what the different terms within the GRF equation truly represent.