At present, suitable methods to evaluate the visual effectiveness of lighting products in the mesopic region are not available. The majority of spectral luminous efficiency functions obtained to date in the mesopic range have been acquired by heterochromatic brightness matching. However, the most recent studies in the mesopic field have adopted a task performance-based approach. This paper summarizes the major mesopic models proposed so far, presenting in detail the experimental conditions of these studies. The authors represent a research consortium which has adopted the task performance-based approach for night-time driving in which mesopic visual performance has been divided into three subtasks. Data for each sub-task will be generated by using a set of common parameter values and 120 observers. The approach and methods used by the consortium are presented.

In non-human primates at least three anatomically and functionally distinct channels convey signals from the retina to the primary visual cortex (V1). Two of these channels, the parvocellular and the koniocellular, are sensitive to chromatic contrasts and form the basis of color vision. In humans, common phylogenetic history with other primates and psychophysical experiments suggest identical retinocortical mechanisms but separate evaluation of the distinct anatomical channels has been difficult because signals are already combined in V1. We studied the spatial distribution of activation to chromatic stimuli along the two opponent chromatic axes in human V1 with multifocal functional magnetic resonance imaging. The signal strength was quantified from three experiments with stimuli up to 20 degrees eccentricity. The hypothesis was that, although the parvo- and koniocellular signals are mixed in V1, distinct distributions of signal strength would be evident. We found that whereas different conditions activated the same areas of cortex, indicating that they have identical magnification factors, the responses to red/green stimulation were stronger close to the fovea whereas the blue/yellow responses were much less diminished with increasing eccentricity. Both chromatic axes showed saturating contrast response functions. Our measure directly from human V1 is in line with earlier psychophysical studies suggesting relatively stronger parvocellular channel representation close to the fovea, and more uniform distribution of the koniocellular and achromatic channels. In addition, our study presents a way to rapidly quantify retinotopic signal transmission in distinct retinocortical pathways of individual subjects.

The spectral sensitivity of the eye at low light levels, ie, mesopic conditions, is determined by the rod and cone photoreceptors of the retina operating together in varying degree as adaptation luminance shifts between the scotopic and photopic. Thus mesopic spectral sensitivity is different from photopic, where only cones contribute to vision. There are definite needs for a practical system of mesopic photometry to be used in assessing light at low light levels, especially in road and other outdoor lighting applications. However, neither of the recently proposed systems of mesopic photometry, the MOVE-model or the X-model, is found satisfactory by common consent of the lighting community. The most active debate has considered the upper luminance limit of the mesopic region, which is regarded to be too high for the MOVE-model and too low for the X-model. The present paper proposes a new modified MOVE-model whose upper luminance limit is adjusted to meet the actual road and street lighting luminance values measured in different weather conditions. The paper compares the MOVE-model, X-model, and the proposed modified MOVE-model with three independent visual performance data sets provided by different European universities. Based on the comparison, recommendations are given for future actions towards internationally accepted practice for mesopic photometry.

Postprandial changes in plasma amino acids were studied in 23 term neonates who had previously been breast-fed ad libitum. As a test meal the infants received from a bottle a weight-based amount of banked human milk (true protein 0.8 g/100 ml) or formula with either 1.5 or 3.0 g of protein (adapted or non-adapted) per 100 ml. As regards the essential amino acids, all rose markedly in the plasma after the feed. The postprandial increments were relatively highest for the branched-chain amino acids, which rose 50-300% above the prefeeding concentrations. Peak values were found after human milk at 30 min but after formulas at 60 min. In extent and duration the rises were directly proportional to the amino acid loads given. This was also true for most semi- and non-essential amino acids, but plasma glycine, in contrast, regularly decreased, and plasma alanine continued to rise until 120 min after the beginning of the feed; neither change correlated with intake. After the milk feeds commonly given to neonates, postprandial alterations in plasma amino acids seem to be highly predictable.