Cercospora kikuchii (Tak. Matsumoto & Tomoy.) M.W. Gardner 1927 is an ascomycete fungal pathogen that causes Cercospora leaf blight and purple seed stain on soybean. Here, we report the first draft genome sequence and assembly of this pathogen. The C. kikuchii strain ARG_18_001 was isolated from soybean purple seed collected from San Pedro, Buenos Aires, Argentina, during the 2018 harvest. The genome was sequenced using a 2 × 150 bp paired-end method by Illumina NovaSeq 6000. The C. kikuchii protein-coding genes were predicted using FunGAP (Fungal Genome Annotation Pipeline). The draft genome assembly was 33.1 Mb in size with a GC-content of 53%. The gene prediction resulted in 14,856 gene models/14,721 protein coding genes. Genomic data of C. kikuchii presented here will be a useful resource for future studies of this pathosystem. The data can be accessed at GenBank under the accession number VTAY00000000 https://www.ncbi.nlm.nih.gov/nuccore/VTAY00000000.
Based on the precedent discovery of a weak antifungal indole isolated from Aporpium caryae, which increased its activity when changing the N-alkyl chain, nineteen N-alkyl
Late season diseases cause yield reductions to soybean grown worldwide. In Argentina, fungicide mixtures composed of quinone outside inhibitors (QoIs) and demethylation inhibitors (DMIs), and the newly introduced succinate dehydrogenase inhibitors (SDHIs), have been effective in managing these diseases. Nevertheless, the risk of selecting strains with resistance to these classes of fungicides is considered to be high. This preliminary study was carried out to determine in vitro sensitivities as determined by the effective concentration that inhibited 50% of radial mycelial growth (EC 50 values) of Cercospora kikuchii, Colletotrichum truncatum and Phomopsis phaseoli to selected QoI and DMI fungicide mixtures. The results indicated that EC 50 values ranged from 0.0065 to 0.0402 μg/ml for C. kikuchii, from 0.0344 to 0.1744 μg/ml for C. truncatum and from 0.0001 to 0.1974 μg/ml for P. phaseoli. To better study the possible resistance against these pathogens, future tests should consider several isolates for each pathogen from different production areas and different fungicide active ingredients.
Aspergillus flavus is the second-most common Aspergillus species isolated from human infection and the second leading cause of invasive and non-invasive aspergillosis in tropical countries, predominantly in Asia, the Middle East and Africa. 1 The treatment of aspergillosis typically involves a primary therapy with triazole antifungals. 2 Additionally, triazoles are an important group of successful fungicides used for more than 40 years to control fungal phytopathogens in agriculture owed to their effectiveness in a broad range of fungi. 3 These antifungals target fungal 14-α sterol demethylases (CYP51s), key enzymes in the biosynthetic
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