Objective: The aim of this study is to review the current evidence on the vertical transmission of SARS CoV-2. Methods: Combination of the following keywords; COVID-19, SARS CoV-2, placenta, vertical transmission, intrauterine infection, breast milk were searched in databases. Results: In the 50 studies included, 17 newborns testing positive for SARS CoV-2 by RT-PCR were reported. In three neonates, SARS-CoV-2 IgG and IgM levels were elevated. Eight placental tissues testing positive for the virus were reported. Three positive RT-PCR results of test of breast milk have been reported recently. One amniotic fluid testing positive was reported. Conclusion: Possible vertical transmission of SARS CoV-2 has been observed in some studies currently. More RT-PCR tests on amniotic fluid, placenta, breast milk and cord blood are required.
The global pandemic infectious disease that was named the new coronavirus disease (COVID 19), spread throughout the world, causing a major public health emergency. The causative virus of COVID-19, called SARS CoV-2, can infect all age groups. Various clinical signs and symptoms have been observed in neonates, children, and adolescents during the COVID-19 outbreak. The clinical manifestations of COVID-19 might be different due to the medical conditions and comorbid status in elderly and pediatric patients. The rise in cases among children has been reported during the COVID-19 pandemic. Although infected children generally appear to be asymptomatic or have only mild symptoms, COVID-19 in children may also involve a wide spectrum of clinical manifestations ranging from asymptomatic carriers to life-threatening and fatal diseases, as COVID-19 is a systemic disease that can affect multiple organs. Due to the lack of knowledge in the current literature, it is necessary to describe the atypical clinical features, including extrapulmonary manifestations, in pediatric patients with COVID-19. This review is conducted to identify knowledge gaps regarding the broad spectrum of clinical signs and symptoms of children with COVID-19.
Aralık 2019'da, Çin'in Wuhan kentinde etiyolojisi bilinmeyen bir grup pnömoni vakası bildirildi. COVID -19 olarak adlandırılan, hayatı tehdit eden bu hastalığa şiddetli akut solunum yolu sendromu koronavirüs-2 (SARS-CoV-2) neden oldu ve enfeksiyon diğer ülkelere bulaşarak tüm dünyaya yayıldı. COVID 19lu gebeler ve yenidoğanlar ile ilgili mevcut veriler sınırlıdır ve COVID-19'lu yenidoğan ve çocuklar için yönetim, yetişkin deneyimine dayanır. Bu makalede, yenidoğanlarda ve gebelerde COVID-19 enfeksiyonu hakkındaki güncel literatür incelendi ve COVID-19 enfekte yenidoğan ve gebelerin yönetimi, klinik bulguları, tanı, tedavi stratejileri ve emzirme ile ilgili önemli noktalar özetlendi.
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