Maluku is one of the archipelago province in Indonesia that has small pelagic fish resources with widespread distribution, such as lompa (Thryssa baelama Forsskål). One of lompa habitat in Mollucas is in Apui coastal areas. The presence of lompa depends on physical and chemical parameters in the waters. This study aims to determine the influence of physical and chemical parameters on the presence of lompa in Apui coastal area Central Mollucas. This study was conducted in June - July 2015. This research is ex-post facto using the value of Environmental Water Quality Index which refers to US-National Sanitation Foundation-Water Quality Index (NSF-WQI). Physical and chemical parameters measured include temperature, velocity, depth, brightness, salinity, pH and dissolved oxygen. The results of calculations with the Indeks Mutu Lingkungan Perairan (IMLP) are 95.61; 92,15; 88.61; 96,37; 93,76; 79.57. And the results of lompa fishing were 181, 162, 205, 173, 184, and 97 respectively. The research conclusion is that the Apui coastal areas are in good condition and potential as lompa habitat.
One of the downstream products which can be synthesized from culilawan oil is an analog curcumin compound (AKS) with a dioxolane ring. AKS products can be synthesized using conventional and microwave methods. The method of synthesis can influence physical properties, compound geometry, and pharmacological effects. The purpose of this study was to determine the effect of the processing method on the hepatoprotective ability of AKS, and to determine a protective dose. AKS was synthesized using insulated safrole compounds from Lawang oil and involved isomerization, oxidation, and aldol condensation of curcumin analogues. At the final stage of the analog curcumin synthesis process, 2 different methods were employed: the conventional method heated the chemical in a water bath at 30 °C for 3 hours, the microwave method heated the chemical using 140 watts of power for 2 minutes. Analogs were tested in vivo in mice (Mus musculus L.) with CCl4 induced liver damage. Hepatoprotective efficacy of AKS products processed by the conventional method and the microwave method were compared using histology and liver enzyme (AST and ALT) assessment. Animals treated with conventionally produced AKS products had lower AST and lower ALT levels—and fewer histological signs of liver damage at a lower dose of AKS—than seen in either untreated animals or those treated with microwave produced AKS. Thus, products that are processed by conventional methods are more hepatoprotective.
Kualitas benih ikan sangat ditentukan oleh deposisi nutrien dalam oosit yang sedang berkembang dan diproduksi oleh hepatosit di bawah kendali hormon estrogen. Penelitian ini bertujuan untuk mengevaluasi peranan suplementasi analog kurkumin dalam meningkatkan kinerja hati untuk mendukung reproduksi ikan nila merah (Oreochromis niloticus). Rancangan yang digunakan adalah rancangan acak lengkap dengan tujuh perlakuan dan tiga kali ulangan, yaitu P0 (kontrol/0 mg kurkumin), P1 (analog kurkumin dosis 2,4 mg/100 g pakan), P2 (analog kurkumin dosis 4,8 mg/100 g pakan), P3 (tepung kunyit dosis 25 mg/100 g pakan), P4 (tepung kunyit dosis 50 mg/100 g pakan), P5 (kurkumin murni komersial dosis 2,4 mg/100 g pakan), dan P6 (kurkumin murni komersial dosis 4,8 mg/100 g pakan). Tiap ulangan terdiri dari 5 ekor ikan. Parameter yang diamati adalah kadar vitelogenin plasma, DNA, dan RNA jaringan hati, kadar serum glutamic pyruvic transaminase (SGPT), serum glutamic oxaloacetic transaminase(SGOT), malondialdehyde (MDA) dan superoxide dismutase (SOD) pada jaringan hati. Hasil penelitian menunjukkan bahwa suplementasi analog kurkumin dalam pakan dapat meningkatkan pertumbuhan jaringan hati ikan nila, terbukti dengan peningkatan konsentrasi DNA dan RNA jaringan hati pada kelompok ikan yang diberikan perlakuan. Peningkatan kinerja hati melalui penurunan konsentrasi MDA, SGPT, dan SGOT serta meningkatnya konsentrasi SOD. Suplementasi analog kurkumin dapat meningkatkan kapasitas hati untuk menyintesis vitelogenin yang akan disimpan dalam folikel yang sedang berkembang selama kematangan gonad.
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