Thirty patients with thalassemia major receiving repeated blood transfusion were studied to see their serum parathyroid hormone (PTH) and calcium status. Serum PTH, serum and 24 h urinary calcium, and serum alkaline phosphatase, phosphorus, and albumin-corrected calcium levels were determined. Half of these patients, in addition to transfusion, were also supplemented with vitamin D (60,000 IU for 10d) and calcium (1500 mg/day for 3 months). Serum PTH, and serum and 24 h urinary calcium concentrations of the patients receiving transfusions were found to be significantly reduced while their serum alkaline phosphatase, phosphorus, and albumin-corrected calcium levels were not significantly altered when compared to the respective mean values for the control group. Vitamin D and calcium supplementation significantly increased their serum PTH and calcium levels. Supplementations also increased urinary excretion of calcium. The results thus suggest that patients with thalassemia have hypoparathyroidism and reduced serum calcium concentrations that in turn were improved with vitamin D and calcium supplementation.
Soon after the discovery of lasers in the 1960s it was realized that laser therapy had the potential to improve wound healing and reduce pain, inflammation and swelling. Today, dentists have a variety of wavelengths to choose from the growing industry of lasers. Also, the field has broadened to include light-emitting diodes and other light sources, and the range of wavelengths used now includes many in the red and near infrared. Each wavelength has a unique interaction with the target tissues of the oral cavity. Laser dentistry, formerly embraced only by the speciality of oral and maxillofacial surgery, now, is positively affecting every field of dentistry. From pediatric and operative dentistry to periodontics, prosthetics to cosmetics and implantology, lasers have made a tremendous impact on the delivery of dental care in the 21st century and will continue to do so as the technology continues to improve and evolve. As low level lasers are more biocompatible than hard lasers, they are evolving rapidly. This article discusses low level laser therapy technology, its dosage, their application in every field of dentistry and risks associated with them, so that they can be used in delivery of superior dental care.
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