Background: Sigmoid volvulus occurs when the sigmoid colon twists on its mesentery and is a cause of intestinal obstruction. Method: This was a descriptive study conducted at the Surgery department of Rajshahi Medical College Hospital during the period from May 2009 to June 2011. Ethical consideration was taken from all the patients. The sample size was 50 with acute sigmoid volvulus. Data were processed and analyzed through SPSS (Statistical package for social sciences). A value of p ≤0.05 was considered significant statistically. Result: Most patients (56%) were diagnosed with acute sigmoid volvulus from the age range of 51-60, among whom male patients had a prevalence (92%). Most of them (92%) were economically impoverished. 36% of patients came to the hospital for treatment from 37-48 hours of illness. The post-operative complication was mild due to wound infection in 10% of patients. Hospital stay was 8-10 days for 76% of patients without complications postoperatively and 11-13 days for 14% of patients. Severe complication Resulting in hospital stay was seen in 4% of patients. Conclusion: Emergency resection of the sigmoid colon and anastomosis in unprepared bowel was an attractive and preferred option in a setting where patients are poor, hospital care often unaffordable and hospital beds are few. TAJ 2022; 35: No-2: 13-18
Introduction: Splenectomy has long been used to treat benign hematological abnormalities such as immune thrombocytopenia (ITP), some hemolytic anemias- especially hereditary spherocytosis and thalassemia, and prehepatic portal hypertension. The discovery that splenectomized individuals are more vulnerable to encapsulated organism infection has been attributed to the spleen's lack of filtration and the development of anticarbohydrate antibodies. Recent research in such splenectomized patients suggests that the lack of this specific anticarbohydrate antibody in these participants is attributable to a decreased number of Memory B cells (a subgroup of B lymphocytes in charge of T-independent responses). Traditional vaccinations, which are given to splenectomized patients to protect them from being infected by encapsulated organisms, can only act in the presence of both the spleen and its functioning marginal zone. As a Result, the study will look at the level of memory B cells in the blood after three months and 1-year post-splenectomy. Aim of the study: The objective of the study was to observe the short- and long-term effects of splenectomy on memory B cells in children. Methods: This prospective case-control study was conducted at the Pediatric Surgery Department of Bangabandhu Sheikh Mujib Medical University, Bangladesh. The study duration was one year, from July 2015 to August 2016. A total of 26 children were selected through a purposive sampling technique for this study, where the control group consisted of 10 children, and the case group consisted of 16 splenectomized children. Result: Among the case group participants, 56.25% were from the oldest age group of 12-15 years, and 37.5% were from the age group of 8-11-years. Male prevalence was high in both the control and the case group. Beta thalassemia was the primary indication for splenectomy for 81.25% of case group patients. Mean B lymphocyte was 39700.2 in the control group, 3655.3 at the 3-month follow-up of case group participants, and 3381.7 for those who had follow-up1-year after splenectomy. The mean amount of IgM memory B cells in the control group was 17.92%; at the 3-month follow-up of the case, it was 18.96%, and at the 1-year follow-up, it was 4.34%. Conclusion: In post-splenectomy individuals, immunological constitutions in memory B cells do not support a T-independent response and, therefore, vaccination. TAJ 2022; 35: No-1: 39-44
Introduction: Colposcopy is done to detect cervical cancer and changes that may lead to cervical cancer. We aimed our study to observe the incidence of different pathologies of the cervix in Colposcopic specimens in Rajshahi Medical College of Bangladesh. Materials and Methods: Retrospective data were collected from the routine histopathological laboratory in the department of pathology Rajshahi Medical College and were recorded during a study period of 1 year (July 2019 to June 2020). Observations: Colposcopic biopsy is one of the commonest diagnostic procedures for assessing cervical Pathosis. Out of 641 specimens more than half, 365 specimens (56.50%) were Chronic Cervicitis. In present study, Chronic Cervicitis with squamous metaplasia and Invasive squamous cell carcinoma became the 2nd, 16.39% (105 specimens), and 3rd, 13.42% (86 specimens) most pathology involving the cervix. Cervical polyp, Endocervical and Leiomyomatous constitute 6.39% and 1.57% of the specimens respectively. 4.36% (28 specimens) of the study sample were the Intraepithelial neoplasia (CIN I, CIN II, CIN III). Adenocarcinoma and Clear cell carcinoma constitute 0.79% and 0.16% of the study specimens. 50 % of the cervical squamous cell carcinoma was moderately differentiated and well-differentiated and poorly differentiated squamous cell carcinoma constitutes 30.23% and 19.77% respectively. Conclusions: Colposcopic examination of cervical biopsy specimens helps to detect the exact causes and underlined pathology
This retrospective study of histopathological specimens was done at the Department of Pathology of Rajshahi Medical College, Bangladesh, from July 2019 to June 2020, emphasizing challenges and diagnosis outcomes. Data obtained from their case notes included age at admission, the site from where the specimens were collected, and histopathological diagnosis. Out of the 2026 histopathology samples, chronic cervicitis constitutes about 50% of the cases. Serous cystadenoma (about 1/4th cases) was common among ovarian pathology. 54.16% of the breast pathology exhibited Invasive ductal carcinoma. Reactive follicular hyperplasia and lymphoma constitute 49.44% of the lymph node pathology. About 80% of the gall bladder pathology was chronic cholecystitis, and metastatic adenocarcinoma was the commonest pathology involving the liver. Squamous cell carcinoma constitutes about 40% of the skin pathology. Osteosarcoma, osteochondroma, and giant cell tumor were the common pathologies involved in bones. Transitional cell carcinoma constitutes about 45% of urinary bladder pathology, and renal cell carcinomas were the commonest pathology of the kidney. Adenocarcinoma constitutes about 45 % of stomach pathology, 28% of small intestine pathology, and 14% of large intestine pathology. Histopathological specimens at the pathology Rajshahi Medical College department with a wide range of pathologies are a major problem. From this study necessity of screening programs for early cancer detection appeared as a time-demanding issue. TAJ 2021; 34: No-1: 16-25
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