In this paper, we present a deterministic mathematical model of monkeypox virus by using both classical and fractional-order differential equations. The model includes all of the possible interactions that contribute to disease spread in the population. We investigate the model’s stability results in the disease-free case when R
0 < 1. When R
0 < 1, we show that the model is stable, otherwise it is unstable. To obtain the best fit that describes the dynamics of this disease in Nigeria, the model is fitted using the nonlinear least square method on cumulative reported cases of monkeypox virus from Nigeria between January to December 2019. Furthermore, adequate conditions for the existence and uniqueness of the solution of the model have been proved. We run numerous simulations of the proposed monkeypox model with varied input parameters to investigate the intricate dynamics of monkeypox infection under the effect of various system input parameters. We investigate the system’s dynamical behavior to develop appropriate infection control policies. This allows the public to understand the significance of control parameters in the eradication of monkeypox in the population. Lowering the order of fractional derivatives has resulted in significant modifications. To the community’s policymakers, we offered numerous parameters for the control of monkeypox.
In this paper, a deterministic mathematical model of the Dengue virus with a nonlinear incidence function in a population is presented and rigorously analysed. The model incorporates control measures at the aquatic and adult stages of the vector (mosquito). The stability of the system is analysed for the disease-free equilibrium and the existence of endemic equilibria under certain conditions. The local stability of the Dengue-free equilibrium is investigated via the threshold parameter (reproduction number) that was obtained using the next-generation matrix techniques. The Routh-Hurwitz criterion, along with Descartes' rule of signs change, established the local asymptotically stability of the model whenever R 0 < 1 and was unstable otherwise. The comparison theorem was used to establish the global asymptomatically stability of the model.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.