Summary This article is the second in a review series about the use of glucocorticoids to treat medical and musculoskeletal conditions in horses. This segment in the series summarises reported dosages, methods of administration and the efficacy of glucocorticoids for various systemic diseases in equids. The most common use of systemic glucocorticoids reported in the literature for management and treatment of alterations of the respiratory, integumentary, immune and neurological systems are included.

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