Research supported by Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) and Fundação de Amparo à Pesquisa do Estado de Minas Gerais (FAPEMIG). The authors have nothing to disclose.
high E2 levels while others failed to find such an effect. Most of the studies observed E2 concentrations attained on the day of hCG administration rather than the area under the curve for E2 concentrations which is expected to reflect more accurately the amount of E2 produced during COH.In this report we studied the relationship between AUC for E2 and E2 concentration on the day of hCG administration for E2 concentrations attained during COH in patients undergoing IVF-ET.Design: Retrospective study. Materials and Methods: Retrospectively we analyzed data from 313 patients who completed one IVF-ET cycle each. We sorted the patients according to the AUC for E2 levels comparing each patient's own AUC with the corresponding E2 concentration on the day of hCG administration.Results: Although the overall AUC for E2 concentrations positively correlated with the E2 concentrations attained on the day of hCG administration, there was no uniform correlation between successive individual patients. Figures 1 and 2 show representative E2 concentrations in two samples (pregnant and non-pregnant cycles), each consisted of 21 patients selected around the mean levels of AUC.
P-56Frank discussions of longevity are important prior to addressing the fertility needs of HIV-1 seropositive patients.
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