The aim of this study was to evaluate the antimicrobial activity of restorative materials - Fuji II LC, Ketac-Fil, Ketac-Molar, Vidrion R, Fuji IX, Ariston pHc, Degufill Mineral, Z100 and Compoglass. For this purpose the agar diffusion test was used determining the bacterial growth inhibition halo over Streptococcus mutans, Streptococcus sobrinus, Staphylococcus aureus and Micrococcus luteus. The materials were prepared and manipulated under aseptic conditions, following the manufacturer instructions. The specimens were immersed in media (Mha and BHIa) that presented the microorganisms. After a 2 h pre-incubation period, at room temperature the plaques were incubated at 37 °C for 48 h. After that, the presence or absence of bacterial growth inhibition halo was verified. Vidrion R and the liquid component of all glass ionomers tested showed antimicrobial activity. However, the resin composite and the "compomer" did not show any antimicrobial activity. In conclusion, only the glass ionomer cement Vidrion R showed antimicrobial activity
A clear understanding of the epidemiology of Candida infection seems to be important, because even when successfully treated, recurrence is very common. The objective of the present study was to evaluate the influence of yeast density for clinical signs of development of oral candidiasis. Oral mucosa was examined for clinical signs of candidiasis, and pooled unstimulated saliva from 100 volunteers, was used for the evaluation of Candida density. No treatment or intervention was made at this point, but the relative risk for candidiasis development was calculated. The results pointed that yeast density may be a major factor in the development of candidiasis relative risk = 12.17 when Candida density is >1x10³. Among associated factors, the higher relative risk was the presence of prosthesis; followed by: 1) individuals >45 years of age, 2) women, 3) people with compromised general health and/or on medications. The results support the hypothesis that predisposing conditions are significant in Candida species carrier status, but the density of Candida may be the primary factor for the development of candidiasis. Because of these results we suggest that the density of Candida must be carefully controlled in patients presenting predisposing factors.
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