Introduction: Osseous dysplasia is a benign tumor of the jaws predominantly occurring in melanoderm women. The pathogenesis remains unknown. Its often fortuitous discovery usually is in the fourth decade of life. Its treatment involves surgery. Our aim was to report a case of osseous dysplasia secondary infection in Senegal. Observation: The over sixty-year-old patient initially came for recurring old suppuration. A prior history of dental avulsions and self-medication was found out. The clinical features were predominant chronic osteitic manifestations. Its radiologic presentation suggested a florid form. The combination of spiramycin-metronidazole had to be given twice. The isolated sequestrum was enucleated and the anatomopathology confirmed the diagnostics. Discussion: The patient's age conformed to late discovery due to silent progression and poor access to medical care. The prior iatrogenic avulsions can be explained by the absence of systematic radiological exploration and by the unawareness of the inconspicuous tumor. The clinical and radiological features at this stage of the osseous dysplasia secondary infection were typical. The treatment and the follow-up were dependent on the prevailing work conditions. Conclusion: The chronic osteitic manifestations are indicative of osseous dysplasia in elderly women in Senegal.
The central giant cell granuloma (CGCG) of the jaws is a rare benign tumour of the mandible (lower jaw) and the maxilla (upper jaw) characterized by destruction of the bone, loss of symmetry of the face and displacement of teeth and tooth germs, especially in younger patients. It is asymptomatic and present with slow growth often accompanied by dental mobility. The removal of this tumour is mutilating and is followed prosthetic rehabilitation. The aim of this study was to report a case of central giant cell granuloma localizated to the symphyseal region in a young patient. The case reported is that of a 14-year-old girl who received a consultation for a tumor in the symphysical region causing an aesthetic impact. The tumor was firm, painless and had been developing for about a year. The cortical were broken in places, in transverse, sagittal and coronal sections. The treatment consisted of her excision under general anesthesia causing a significant loss of substance. The tumor mass, very hemorrhagic, was extended to the buccal floor. At the end of the intervention, a significant loss of substance was observed. Two months later, a partial adjunct prosthesis was performed. The anatomo-pathological examination showed of several multinucleated giant cells, a few histiocytes, lymphocytes and fibroblasts. The removal of this aggressive tumour remains mutilating, with significant psychological repercussions. More recently, antiangiogenic therapy with interferon alpha has been successfully applied.
The objective was to study the epidemiological, clinical and radiological aspects of patients with mandibular fractures in the odontostomatology department at the General hospital Idrissa Pouye in Senegal. This was a retrospective study of the records of patients who came for a mandibular fracture during the period from February 2007 to June 2019 to the odontostomatology department of the General hospital Idrissa Pouye in Dakar. The inclusion criterion was any patient file containing complete information and presenting a mandibular fracture received in the odontostomatology department. We used sociodemographic, clinical and radiographic variables. Of 128 patients who came for consultation with a mandibular fracture, 115 were male and 13 were female. The age group most affected was between 21 and 30 years. Workers (25.2%), pupils and students (25.2%) were the most represented. The most frequent cause of mandibular fractures was road traffic accidents (36.71%). In 41% of the road accidents, Jakarta mopeds were involved. The diagnosis was confirmed by radiological examination, which consisted of an orthopantomogram in 83.5% of cases. The mandibular symphysis was the most frequent location with 40.3% of fracture sites. Total continuity of the lines was observed in 21.9% of cases.
The aim of the present study was to investigate the Ki67 expression level and to measure the cell proliferation index (Ki67) in odontogenic benign tumors.This was an analytical cross-sectional study of odontogenic benign tumors. The sampling was non-probabilistic with an exhaustive recruitment including all biopsy or surgical excision specimen of odontogenic benign tumors. Ki67 immunohistochemistry was performed on histological sections of paraffin-fixed tissues of 3µ thickness with the Ki67 (MM1) monoclonal antibody. The studied variables were sociodemographic, clinical and histopathological. The data have been analysed with SPSS 20.0 software.: Ameloblastoma represented 50.9% of cases and cemento-osseous dysplasia 36.4%. Among the 28 ameloblastoma cases, the 15 (53.6%) were plexiform type, the 7 (25%) follicular type and the 6 (21.4%) unicystic type. The percentage of Ki67 labelled cells was less than 1% in 74.6% (n=41) of the tumors and was equal to 5% in 12.7% (n=7) of cases. A Ki67 law labelling was found in 87.3% (n=48) of tumours and a negative labelling in 12.7% (n=7) of cases. The odontogenic benign tumors had a weak Ki67 expression level and a low epithelial cell proliferation index. The Ki67 could not therefore be used as a predictive biomarker of tumor cell proliferation and the risk of recurrence in odontogenic benign tumors.
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