Rare-earth elements (REEs) are used in a growing number of applications, and their release to environment has increased over the decades. Knowledge of REEs in human milk and factors that could possibly influence their concentration is scarce. This study evaluated the concentrations of 16 REEs (Ce, Eu, Er, Gd, La, Nd, Pr, Sc, Sm, Dy, Ho, Lu, Tb, Tm, Y, and Yb) in human colostrum milk collected from Polish women (n = 100) with the ICP-OES technique. The concentrations (mean ± SD) of Pr (41.9 ± 13.2 μg L −1 ), Nd (11.0 ± 4.0 μg L −1 ), La (7.1 ± 5.2 μg L −1 ), and Er (2.2 ± 0.8 μg L −1 ) were found above detection limits. The total mean ± SD concentration of detected REEs was 60.9 ± 17.8 μg L −1 . Current smokers displayed significantly increased Nd concentrations compared to women who had never smoked. No other associations between REEs in colostrum milk and age, diet in pregnancy (food supplement use and frequency of fish, meat, and vegetable consumption) or place of living (urban/rural) were found. This study adds to general understanding of the occurrence and turnover of REEs in women and human fluids.
The rusty pipe syndrome is an uncommon condition. It is characterised by suddenly painless, bilateral bloody nipple discharge with no visible evidence of mechanical injuries within the breasts. It resolves spontaneously with no additional medical intervention. If the problem persists for more than 5-7 days, further investigations should be made to exclude other pathologies. In the available literature, there is no clear explanation of the condition. Many authors agree that the condition may be caused by the structure of blood vessels and may depend on changes therein that occur during stage I and II lactogenesis. In most cases, it is recognised during breast milk expression, when the colour of milk is different than normally.
The phenomenon described in the literature as rusty pipe syndrome is a rare condition (the estimated incidence is 0.1% in the population of breastfeeding women) where the prenatal milk and the colostrum are rust- or blood-colored. Due to the rare occurrence of this phenomenon and the related nature of the baby’s regurgitated discharge—green, brown or blood-stained, there is a general fear of latching a newborn or continuing to breastfeed if the regurgitation persists. In this care report, a patient’s milk was tested to determine its microbiological and morphological content. No significant abnormalities were noted in these tests. The nutritional profile of the blood-stained colostrum was normal. Breast milk has an indisputably invaluable impact on the newborn’s further development and there is no connection between rusty pipe syndrome, as described in the literature, and any clinical complications. This is crucial to encourage mothers to keep breastfeeding even if they observe blood-stained colostrum.
Purpose: synthetic oxytocin is currently used to induce labor and strengthen the contractile function in the first or second stage of labor. It is also used therapeutically and prophylactically in the third stage of labor. We aimed to correlate the dose and duration of synthetic oxytocin infusions used during induction of labor, augmentation of labor in the first and second stage of labor, and during active management of labor in the third stage of labor to the level of prolactin and cortisol in the serum of the parturient blood and from the umbilical cord vein.Methods: The mother’s blood was collected from a venous vessel and foetal from the umbilical cord vein just cutting was performed and the levels of cortisol and prolactin was evaluated by electrochemiluminescence (ECLIA). The blood sample from the umbilical cord vein and artery were collected to separate heparinized capillaries and the pH, base deficit (BD), pO2, and CO2 concentration were assessed.Results: We observed decreased level of prolactin immediately after the labor depending on the total dose of synthetic oxytocin used. We did not observe any relationship between the level of prolactin on postpartum day 2 on the dose of administered hormone or the fact of the labor induction. We observed significant correlations with regard to hormone levels without the synthetic oxytocin total dosage correlation. Conclusion: We strongly believe that the definition of uniform norms and principles with regard to the dosage of synthetic oxytocin for labor induction should be determined.
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