The manuscript aims at furnishing comprehensive information pertaining specialised coating technology/ processes. Solid dosage forms and solid particulates (SDFSP) are the major contributing group in the solid pharmaceuticals (SoPs). SDFSP exhibit peculiar physico-chemical properties and interaction behaviour which create problems/ issues during their handling, processing, storage, and use. Modifying and/or engineering surface attributes of SDFSP are advocated as powerful tool to modify their interaction behaviour and realise their worthy applications and functionalities. In this regard coating their surfaces with coating material (CM) is novel approach. Said approach involves wet and dry process for realising deposition of CM onto the surface of SDFSP substrates. Both the processes modify and/or alter innate properties of SDFSP substrates either physically or chemically. Basing on involved wet or dry process the coating method is either dry coating method (DCM) or wet coating method (WCM). Accordingly nowadays there available number of specialised devices, that bases on diverse technologies. Amongst them some involves state-of-art process/ technology like Supercell coating technology (SCT), Chemical vapour deposition (CVD), Atomic/molecular layer deposition (AMLD), Electrostatic deposition, Thermo-mechanical process, Resonant acoustic technology, Fluidised-bed process, Supercritical fluid (SCF) technology,  and others. These foundational for commercially availability of specialised equipments like Magnetically Assisted Impaction Coater (MAIC), Resodyn acoustic mixer, Hybridizer®, Theta-composer®. Mechanofusion®, and others. Working and working principle, applicability, benefits, pros and limitations of specialised coating processes and technologies are herein discussed and presented. Contained information hoped to be beneficent for pharmaceutical professionals and technocrats and professionals of allied field. Keywords: Coating, composite product, modification, specialised, surface.

The manuscript aims to provide glimpse on updated information relating thermo-mechanical dry coating processes (TMDCP) suiting in modifying surface attributes of fine and ultra-fine particle (FiUlFiP). FiUlFiPs are the integral component of pharmaceutical processes. They exhibit complex and queer properties, are conferred mostly from their surface attributes colligated with their higher surface area. Particle engineering technocrats extensively working for modifying surface & surface attributes of FiUlFiPs. These efforts are to find their worthy applications & new functionalities. Among available diverse particle engineering technologies/ process, TMDCP, a dry coating process (DCP), advocated being worthy and efficient. The TMDCP finds multidisciplinary applications, mostly in drug development & drug delivery. Said DCP involves fixing and/or attaching coating material (CoM) as particles herein synonym guest particle (GP) onto core/substrate particle (CSP) herein synonym host particle (HP). Attaching/ fixing the GPs onto HPs, in TMDCP, involve their mechanical and/or thermal interactions. Scientific literatures are evidencing diverse techniques and/or process, basing on discussed interactions. Amongst them novel techniques/ processes are Hybridization, Magnetically assisted impaction coating process (MAICP), Mechanofusion, Theta-composer, and high shear compaction. In this area diverse devices/ equipments are prevailing in market. Important are Hybridizer, Magnetically assisted impaction coater (MAIC), Theta-composer, Mechanofusion, Quadro Comil®, Cyclomix®, and many others. Attempt of this article is to discuss and present their method of working, working principle, applicability, limitations, and benefits. Contained information might be beneficial for professionals of pharmaceutical and allied field. Keywords: dry coating, equipment, particles, processes, thermo-mechanical.

The presentation of this work aims to update professionals involved with aqueous film coating (AFC) of pharmaceuticals on facts associated with film coating (FC) based on aqueous solvent (AS). Initially sugar coating (SC) was the first choice of pharmaceutical industry and much time and efforts were spent in perfecting the techniques and processes of SC. Long processing time and demand for operator skill as in SC compelled them to develop FC. The FC of substrate is achieved by spraying solution of diverse polymer in AS or volatile organic solvent (VOS). Initially, use of VOS in the FC is preferred over AS, as latter inherits problems like sticking, picking, over-wetting, and many more. Momentum for using AS based FC and replacing the VOS based one with the aqua based one got accelerated from last few decade for reasons like safety, toxicity, stricter regulation on environmental pollution, and economy. Nowadays coating techniques & process relies mostly on AS due to its significant benefits over VOS. Functional properties of the film-coated pharmaceuticals depends greatly on film forming polymer (FFP) along with other factors like process, equipment, technology, additives, and many others. Summarised information on technical aspect of AFCs is rare, necessitating this work. Thus information gathered, summarised, studied, and hereby is attempting to be presented in a convenience way for enriching stakeholders in the pharmaceutical field. The presentation is for updating professionals in this regard. Key words: Aqueous, dispersion, film-coating, latex, polymer.

Presentation of manuscript is aiming to furnish glimpse on coating processes. Coating is process of snugly covering substrate surface with coating materials (CoM). In due course coating process has gradually developed from sugar-coating to non-aqueous film-coating to aqueous film-coating to specialised-coating processes. In second half of past century sugar-coating was first choice for pharmaceutical industry. Lengthy and tedious processing along with issues of skilled-operator inherited to sugar-coating compelled them to spring-up and improve film-coating. From past five decades, volatile organic solvent (VOS) are preferred over water in film-coating. Momentum for using aqueous solvent in film-coating gets accelerated from past few decades. Nowadays these replacing the VOS based film-coating processes as later inherit issues relating toxicity; safety; worker hygiene & safety; environmental pollution; etc. During process of finding novelty of coating another exploited sphere is coating of particulate substrate surfaces with CoM is to confer them worthy functionalities and applications. In this area both wet- & dry-coating process finds applicability thru modifying and/or altering innate properties of substrate, physically and/or chemically. Dry-coating process basically comprises specialised and novel process & technologies. Nowadays there available numerous conventional, specialised, and novel coating processes. Amongst them state-of-art process are hot-melt coating (HMC) process, aqueous film-coating process, aerosolized coating process, Supercell® coating process, gas-/ vapour-phase process, photo curable coating process, electrical-electrostatic deposition process, Resonant acoustic coating process, thermal and mechanical process, thermo-mechanical process, fluidised-bed processes, etc. Herein conventional, specialised, and novel coating processes are briefed, to update professionals. Keywords: Coating, film-coating, novel, process, specialised.

Probiotic microorganisms explored for delivering associated proclaimed valuable benefits and its market is expanding in diverse sphere. Probiotics (PRs) are presented as pharmaceutical, dairy, non-dairy, and personal care products. To improve performances and marketplace survival of these products, diverse methods and technology devised. Amongst them microencapsulation (MEC) is widely explored to get product with wished and improved performances. Interest evoke for marketing of product containing microencapsulated probiotics (PCEP) to upkeep performance, reproducible, throughout its life cycle. The review features on prospective action plan for evolution of PCEP including method for combating issues. Presented information will be a helping hand for developers to get PCEP, with excellent feature and performance, and improved marketability.