BackgroundLifetime stroke risk has been calculated in a limited number of selected populations. We determined lifetime risk of stroke globally and at the regional and country level.MethodsUsing Global Burden of Disease Study estimates of stroke incidence and the competing risks of non-stroke mortality, we estimated the cumulative lifetime risk of ischemic stroke, hemorrhagic stroke, and total stroke (with 95% uncertainty intervals [UI]) for 195 countries among adults over 25 years) for the years 1990 and 2016 and according to the GBD Study Socio-Demographic Index (SDI).ResultsThe global estimated lifetime risk of stroke from age 25 onward was 24.9% (95% UI: 23.5–26.2): 24.7% (23.3–26.0) in men and 25.1% (23.7–26.5) in women. The lifetime risk of ischemic stroke was 18.3% and of hemorrhagic stroke was 8.2%. The risk of stroke was 23.5% in high SDI countries, 31.1% in high-middle SDI countries, and 13.2% in low SDI countries with UIs not overlapping for these categories. The greatest estimated risk of stroke was in East Asia (38.8%) and Central and Eastern Europe (31.7 and 31.6 %%), and lowest in Eastern Sub-Saharan Africa (11.8%). From 1990 to 2016, there was a relative increase of 8.9% in global lifetime risk.ConclusionsThe global lifetime risk of stroke is approximately 25% starting at age 25 in both men and women. There is geographical variation in the lifetime risk of stroke, with particularly high risk in East Asia, Central and Eastern Europe.

Bacterio-pathological investigation on 1751 dead chickens during one year period from January to December 2002 at the BRAC Poultry Disease Diagnostic Centre, Gazipur showed that 39.81% (n=697) cases with seven types of different bacteriological diseases of which salmonellosis (n=385), colibacillosis (n=147) and fowl cholera (n=114) were found significantly higher rate of prevalence then staphylococcosis (n=6),  gangrenous dermatitis (n=17), necrotic enteritis (n=24) and infectious coryza (n=4). Accordingly, avian salmonellosis, colibacillosis and pasteurellosis were selected for detailed investigation. Age wise prevalence of avian salmonellosis showed highest infection rate in adult layers (53.25%) in comparison to brooding (14.55%), growing (16.10%) and pullet (16.10%) chickens. The avian colibacillosis was found widely prevalent in all age groups of chickens (9.52 to 36.73%) with specially high prevalence rate in adult layer birds (36.73%). Fowl cholera was recorded in chickens more than two weeks of age with significantly (p < 0.01) highest occurrence in adult chickens. Seasonal influence showed significantly (p < 0.01) highest proportionate prevalence of salmonellosis during summer (48.05%) in comparison to rainy (28.31%) and winter (23.66%) seasons. Colibacillosis was recorded more or less uniformly in all the three seasons of the year with significantly (p < 0.01) higher rate during summer (40.82%) season. Similarly, the prevalence of fowl cholera was also found significantly (p < 0.01) highest during summer (49.12%) in comparison to rainy (26.32%) and winter (24.56%) seasons. The isolated causative agents of avian salmonellosis (Salmonella pullorum), avian colibacillosis (Escherichia coli) and avian pasteurellosis (Pasteurella multocida) were characterized by bacteriological methods which were also subjected to pathogenicity study in 52-day old broiler chickens. Pathogenicity study showed that the incubation period of these three bacterial diseases were recorded as 96 hours and clinical signs appeared on 4th day of inoculation and observed that S. pullorum, E. coli and P.  multocida resulted 100% morbidity in chickens. Key words: Characterization; pathogenicity; salmonellosis; colibacillosis; pasteurellosis; chickens doi: 10.3329/bjvm.v2i1.1926 Bangl. J. Vet. Med. (2004). 2(1) : 01-08

The high mortality rate of commercial poultry has been encountered as a major problem which discourage farmers and entrepreneurs in this industry in Bangladesh. This study was carried out to determine the role of single and concurrent infections associated with mortality in 1751 commercial chickens during one year period from January to December 2002. Diagnosis of diseases was made on the basis of history, necropsy findings, isolation and identification of causative bacteria and other laboratory tests. The etiological investigations of 1751 dead chickens showed that about 39.81% bacterial, 22.73% viral, 13.65% mycoplasmal, 1.54% fungal, 10.11% parasitic, 31.64% systemic, 3.43% nutritional deficiency and 1.77% other diseases were associated with these mortality. Salmonellosis (21.99%), Colibacillosis (8.40%), Fowl cholera (6.52%), Avian mycoplasmosis (13.65%), Infectious bursal disease (11.20%), Newcastle disease (10.34%) and coccidiosis (6.23%) were recognized as major diseases associated with mortality in commercial chickens in Bangladesh. About 32 diseases were recorded, of which both single (76.30%) and mixed infections as two (21.53%), three (1.83%) and four (0.34%) types were associated with mortality of chickens. Significantly (p < 0.01) highest proportionate mortality rate was recorded in > 20 weeks old adult layer (45.52%) in comparison to > 2 to 8 weeks old grower (24.04%), > 8 to 20 weeks old pullet (18.16%) and up to 2 weeks old brooding (12.28%) chickens. Seasonal influence showed highest mortality rate during Summer (43.06%) in comparison to Rainy (27.81%) and Winter (29.13%) seasons. It may be concluded from this study that both the single and concurrent infections are associated with high mortality rate in commercial chickens in Bangladesh. Therefore, the interactions of different pathogens in naturally occurring diseases should be considered during diagnosis and evaluation of vaccination.  Key words: Occurrence; concurrent; mortality; diseases; chickens DOI = 10.3329/bjvm.v1i1.1911 Bangl. J. Vet. Med. (2003). 1 (1) :  15 - 20

Bovine tuberculosis (bTB) is one of the most prevalent economically important zoonotic diseases and tuberculin test has been widely used to detect its prevalence worldwide. This study used a commercial immunochromatographic assay (ICGA) to detect the prevalence of bTB and to evaluate the differences in milk production between lactating cows with positive and negative results in Bangladesh. Thirty Red Chittagong (indigenous) cattle (RCC) were randomly selected from a herd of 87 RCC maintained at the Bangladesh Agricultural University Dairy Farm (BAUDF), Mymensingh during the period from March to July 2008, of which 30% cattle showed positive reaction to bTB. Of the 30 tested cattle, 35.29% (6/17) lactating cows, 20.0% (1/5) non-lactating pregnant cows, 33.33% (1/3) weaned calves and 20.0% (1/5) unweaned calves showed positive reaction to bTB. The detection of bTB in two calves and their respective mother cows indicates the possible transmission of TB organism through their colostrums / milk. Of the 17 lactating cows, 6 cows had positive and 11 had negative results to bTB. Cows with positive results produced less milk ( mean 1.29 litre / day / cow ) in comparison to cows with negative test ( mean 1.57 litre / day/ cow ) results which appeared as 17.83% reduction of milk production. Further study on the mastitis with or without bTB and its effect on milk production require data of more herds for conclusion of these results.

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