We study the problem of visualizing large-scale and highdimensional data in a low-dimensional (typically 2D or 3D) space. Much success has been reported recently by techniques that first compute a similarity structure of the data points and then project them into a low-dimensional space with the structure preserved. These two steps suffer from considerable computational costs, preventing the state-ofthe-art methods such as the t-SNE from scaling to largescale and high-dimensional data (e.g., millions of data points and hundreds of dimensions). We propose the LargeVis, a technique that first constructs an accurately approximated K-nearest neighbor graph from the data and then layouts the graph in the low-dimensional space. Comparing to t-SNE, LargeVis significantly reduces the computational cost of the graph construction step and employs a principled probabilistic model for the visualization step, the objective of which can be effectively optimized through asynchronous stochastic gradient descent with a linear time complexity. The whole procedure thus easily scales to millions of highdimensional data points. Experimental results on real-world data sets demonstrate that the LargeVis outperforms the state-of-the-art methods in both efficiency and effectiveness. The hyper-parameters of LargeVis are also much more stable over different data sets.

at Austin in USA, was dismantled and shipped to China in 2004, and renamed as the Joint TEXT (J-TEXT) tokamak. The reconstruction work, which included reassembly of the machine and development of peripheral devices, was completed in spring of 2007. Consequently, the first plasma was obtained at the end of 2007. At present, a typical J-TEXT Ohmic discharge can produce a plasma with flattop current up to 220kA and lasting for 300ms, line averaged density above 2×10 19 m-3 , and an electron temperature about 800eV, with a toroidal magnetic field of 2.2T. A number of diagnostic devices used to facilitate the routine operation and experimental scenarios were developed on the J-TEXT tokamak. Hence, the measurements of the electrostatic fluctuations in the edge region and conditional analysis of the intermittent burst events near the last closed flux surface (LCFS) were undertaken. The observation and simple analysis of MHD activity and disruption events were also performed. The preliminary experimental results and the future research plan for the J-TEXT are described in detail.

Although the regulation of taxol biosynthesis at the transcriptional level remains unclear, 10-deacetylbaccatin III-10 β-O-acetyl transferase (DBAT) is a critical enzyme in the biosynthesis of taxol. The 1740 bp fragment 5'-flanking sequence of the dbat gene was cloned from Taxus chinensis cells. Important regulatory elements needed for activity of the dbat promoter were located by deletion analyses in T. chinensis cells. A novel WRKY transcription factor, TcWRKY1, was isolated with the yeast one-hybrid system from a T. chinensis cell cDNA library using the important regulatory elements as bait. The gene expression of TcWRKY1 in T. chinensis suspension cells was specifically induced by methyl jasmonate (MeJA). Biochemical analysis indicated that TcWRKY1 protein specifically interacts with the two W-box (TGAC) cis-elements among the important regulatory elements. Overexpression of TcWRKY1 enhanced dbat expression in T. chinensis suspension cells, and RNA interference (RNAi) reduced the level of transcripts of dbat. These results suggest that TcWRKY1 participates in regulation of taxol biosynthesis in T. chinensis cells, and that dbat is a target gene of this transcription factor. This research also provides a potential candidate gene for engineering increased taxol accumulation in Taxus cell cultures.

Recent J-TEXT research has highlighted the significance of the role that non-axisymmetric magnetic perturbations, so called three-dimensional (3D) magnetic perturbation (MP) fields, play in a fundamentally 2D concept, i.e. tokamaks. This paper presents the J-TEXT results achieved over the last two years, especially on the impacts of 3D MP fields on magnetohydrodynamic instabilities, plasma disruptions and plasma turbulence transport. On J-TEXT, the resonant MP (RMP) system, capable of providing either a static or a high frequency (up to 8 kHz) rotating RMP field, has been upgraded by adding a new set of 12 in-vessel saddle coils. The shattered pellet injection system was built in J-TEXT in the spring of 2018. The new capabilities advance J-TEXT to be at the forefront of international magnetic fusion facilities, allowing flexible study of 3D effects and disruption mitigation in a tokamak. The fast rotating RMP field has been successfully applied for avoidance of mode locking and the prevention of plasma disruption. A new control strategy, which applies pulsed RMP to the tearing mode only during the accelerating phase region, was proved by nonlinear numerical modelling to be efficient in accelerating mode rotation and even completely suppresses the mode. Remarkably, the rotating tearing mode was completely suppressed by the electrode biasing. The impacts of 3D magnetic topology on the turbulence has been investigated on J-TEXT. It is found that the fluctuations of electron density, electron temperature and plasma potential can be significantly modulated by the island structure, and a larger fluctuation level appears at the X-point of islands. The suppression of runaway electrons during disruptions is essential to the operation of ITER, and it has been reached by utilizing the 3D magnetic perturbations on J-TEXT. This may provide an alternative mechanism of runaway suppression for large-scale tokamaks and ITER.

Because they were used for decades to present visual stimuli in psychophysical and psychophysiological studies, cathode ray tubes (CRTs) used to be the gold standard for stimulus presentation in vision research. Recently, as CRTs have become increasingly rare in the market, researchers have started using various types of liquid-crystal display (LCD) monitors as a replacement for CRTs. However, LCDs are typically not cost-effective when used in vision research and often cannot reach the full capacity of a high refresh rate. In this study we measured the temporal and spatial characteristics of a consumer-grade LCD, and the results suggested that a consumer-grade LCD can successfully meet all the technical demands in vision research. The tested LCD, working in a flash style like that of CRTs, demonstrated perfect consistency for initial latencies across locations, yet showed poor spatial uniformity and sluggishness in reaching the requested luminance within the first frame. After these drawbacks were addressed through software corrections, the candidate monitor showed performance comparable or superior to that of CRTs in terms of both spatial and temporal homogeneity. The proposed solution can be used as a replacement for CRTs in vision research.