Drug information service gains its importance as the development of new drugs and new diseases rising in no time and on other side the limited availability of health care resources to provide factual information in handling the new diseases and drugs. The aim of this study is to provide relevant information to the queries and evaluate the quality of the services provided. Prospective analysis was done for a period of 6 months in a south Indian tertiary care teaching hospital. We have interacted directly with health care professional to obtain queries and also communicated them with query boxes. In prospective analysis, A total of 108 queries were responded and identified 31 medication errors among them ,almost 65 % were rectified, 25 % were accepted but could not rectify as prescribers have justified the reason and remaining 10 % were not accepted as an error. 49 % of the requesters were appreciated with good; only 3% were advised to improve the quality. It was found that, the quality of the drug information service is "well accepted" and provides a great opportunity for further improvement with the involvement of more number of healthcare professionals.
Introduction: The utilization of HAMs is crucial in emergency and intensive care departments, as they can cause a significant amount of damage to the patient and health care members if we could not follow the standard treatment guidelines. Drug utilization evaluation/review involves a comprehensive review of the patient’s prescription and medication data before, during, and after dispensing to ensure appropriate medication decision making and positive patient outcomes.
Objective: This study was taken up given finding the utilization patterns and rectifying the issues with the usage of high alert medications (HAMs) and improving their utilization.
Methodology: A cross-sectional study was conducted for 6 months at a south Indian tertiary care hospital. Treatment guidelines were prepared to compare the actual drug use. Data were collected both retrospectively and prospectively by patients and care taker’s interview, medication chart review, and discussion with prescribers and applied WHO DUE indicators to evaluate utilization patterns.
Results: Of 362 cases, 57.73 % were males/ and the majority geriatrics. Among all HAMs Insulin is frequently prescribed (34.5 %) and the costly drug is Enoxaparin. Generic names were used in writing prescriptions and parenteral formulations were mostly used. Around 9 ADRs were identified and managed, and a total of 133 moderate to severe Drug-Drug Interactions were found, of them, only 2 were actual.
Conclusion: With this study, we conclude that the use of HAMs was found to be appropriate as per the guidelines as we observed very few DRPs with the study drugs.
Keywords: HAM, DRP’s, DUE, ICU, DDD
Background: Adverse drug reaction (ADR) is an appreciably harmful reaction from an intervention related to the use of the medicinal product, which predicts hazard from future administration and specific treatment, or alteration of the dosage regimen, or withdrawal of the product. This study aimed to analyze ADRs retrospectively to understand their nature at the study site.
Methods: Retrospective analysis of the ADRs reported over 6 months was conducted at a South Indian Tertiary Care Teaching Hospital.We analyzed Patient characteristics, Causality, Severity,Dechallenge, Rechallenge, Management, Outcomes, Department, Drug Class, and Organ system involved related adverse events.
Results: Out of 116 ADRs females developed 51.72 % of reactions, and ADRs are more common in the adult population (73.2 %), followed by geriatrics (11.2 %). Antibiotics were the most frequently used medication class and also lead to the majority of reactions (16.3%). A total of 55 ADRs were assessed for causality, and 31 (57.4%) reactions were possibly linked to the implicated medications. At the time of reporting, 41 (35.6 %) patients had recovered from the reaction, 37 % of ADRs were non-serious, and no deaths had been reported.
Conclusions: The majority of ADRs were minor, and patients were able to recover from them after discontinuing the implicated medicine. We were unable to estimate the severity of the ADRs using this reporting form, and the majority of ADRs lacked a causation assessment, which is not a mandatory condition for reporting any suspected ADR.
Keywords: ADRs, Retrospective study, Causality assessment, HCPs, Pharmacovigilance program of India.
Recent years have seen a dramatic increase in the usage of renewable energy sources in a variety of industries, including the automotive sector where it plays a role in charging the batteries of electric vehicles (EVs). Here, we present a method for lightweight EVs that uses a solar energy power conversion with SEPIC and bidirectional interleaved DC-DC converter (BIDC) to charge their batteries from the grid instead of on-board. The suggested technology can recharge the electric vehicle's battery throughout daylight and nighttime hours. The EV battery and the backup battery both get charged during peak sunlight hours, and the backup battery helps charge the EV battery when the sun isn't out. In order to test the effectiveness of the proposed charging method, a simulation was run in the MATLAB software using the Simulink application.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.