Drug information service gains its importance as the development of new drugs and new diseases rising in no time and on other side the limited availability of health care resources to provide factual information in handling the new diseases and drugs. The aim of this study is to provide relevant information to the queries and evaluate the quality of the services provided. Prospective analysis was done for a period of 6 months in a south Indian tertiary care teaching hospital. We have interacted directly with health care professional to obtain queries and also communicated them with query boxes. In prospective analysis, A total of 108 queries were responded and identified 31 medication errors among them ,almost 65 % were rectified, 25 % were accepted but could not rectify as prescribers have justified the reason and remaining 10 % were not accepted as an error. 49 % of the requesters were appreciated with good; only 3% were advised to improve the quality. It was found that, the quality of the drug information service is "well accepted" and provides a great opportunity for further improvement with the involvement of more number of healthcare professionals.
Gold nanoparticles have many properties that are attractive for the use in the cancer therapy. They are small and widely penetrate into the body, preferentially accumulating at the tumor sites owing to EPR effect .They can bind many proteins and drugs and can be actively targeted to cancer cells over expressing cell surface receptors. Gold nanoparticle have high atomic number, which leads to greater absorption of kilovoltage Xrays and provide greater contrasts than standard agents. Gold nanoparticles have been shown to cause radio sensitization at kilovoltage and megavoltage photon energies. The factors that affect gold nanoparticle pharmacokinetics, bio-distribution and in-vivo toxicity need to be clarified. Targeted gold nanoparticle need to exit tumour vasculature, cross the tumour intersitium, enter the cells and potentially exit lysosomes to be effective in-vivo. A standard approach for physicochemical characterization and pre-clinical testing needs to be implemented and this process is being aided by the NLC. With intense global interest in nanotechnology and particularly in nanomedicine.
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