Results: At primary analysis, 160 pts were randomised; all pts completed crossover tx; 44% completed continuation tx at cut-off (24-02-20). 136 pts (85%; 95% CI 79e90%) preferred SC; 22 (14%) preferred IV; 2 (1%) had no preference. Main reasons for SC preference: reduced clinic time (n¼119) and comfort during administration (n¼73). 141 (88%) were very satisfied or satisfied with SC vs. 108 (68%) with IV. 87% chose SC to complete HER2-targeted therapy. HCPs' perceptions on median pts' time in the tx room across cycles 1e6 for SC vs. IV admin were 33e50 vs. 130e300 min, respectively. The rates of serious adverse events (AEs) and grade 3 AEs were low; the most common AEs were as expected (table ).
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