Background Intravesical foreign bodies leading to bladder stone and renal insufficiency are rarely reported in literature. Case presentation We report a case of 18-year-old male who presented with renal insufficiency due to bladder outlet obstruction caused by bladder stone formed over electric wire that was self-inserted 1 year ago. We present the symptoms, imaging, diagnosis and treatment of unique complications due to self-insertion of intravesical foreign body. We performed the open vesicolithotomy uneventfully and patient sent for psychiatric evaluation. Our patient’s case was unique for several reasons i.e., inserted foreign body was electric wire, symptoms duration was not very long and it resulted in life threatening complication of renal failure. Conclusion There should be high index of suspicion in young patients with bladder foreign bodies presenting with lower urinary tract symptoms.
A cross-sectional study was conducted to assess the frequency of metabolic disorders detected in 24-hour urine collection in patients with increased morbidity for recurrent upper urinary tract stones. This research was conducted Department of Urology Bakhtawer Amin Hospital, Multan. Study was carried out over a period of six months from 01-12-2021 to 01-06-2022. Total 100 cases presented with the recurrent urinary tract stone were enrolled in this study. Patients were asked about their demographics which include name, age, gender and contact details. A 24-hour urine sample from each patient was analyzed for its contents. Metabolic abnormalities were recorded as per operational definition) . Out of 100 patients, 30 %( n=30) were in age Group of 12-30 years whereas 70 %(n=70) were in age Group of 31-60 years, mean age was calculated as 35.85 ± 9.83 years. Mean duration of kidney stone was 1.69 ± 0.46 months. Frequency of metabolic abnormalities were 42%. We concluded that, the most common 24-hour urine abnormalities were hyperuricosuria (32%), hypercalciuria (19%), hypernatriuria (20%).
An overactive bladder syndrome is a group of symptoms, i.e., frequency, urgency, nocturia, and sometimes accompanied by urge incontinence. The recent pharmacological options are some drugs, mainly used anti-muscarinic. However, anti-muscarinic drugs have different adverse effects, i.e., constipation and dry mouth. In 2011, a β3 receptor agonist, mirabegron, was studied to treat overactive bladder syndrome. This non-randomized trial was conducted in the Department of Urology, Gomal medical college, D.I. Khan, KPK Pakistan. The study was done from June 2018 to January 2022. We divided 4220 patients into two equal groups. Group a used solifenacin 5 mg for 6 weeks, while group B used mirabegron 50 mg for the same duration. We assessed safety and efficacy after 6 weeks. Most of the adverse effects were mild to moderate severity. Dry mouth occurred in 125 patients out of 2110 (5.92%) in group A and 66 out of 2110 (3.12%) in group B. p-value = 0.0001. Constipation occurred in 53 (2.51%) patients in group A and 46 (2.18%) patients in group B. p-value=0.5417. The improvement in overactive bladder symptoms score (OBSS) occurred in 1443 out of 2110 (68.38%) patients in group A and 1409 out of 2110 (66.77%) patients in group B. p-value=0.2778. Based on the results, it can be concluded that Mirabegron has fewer adverse effects than solifenacin, while both drugs are approximately similar in efficacy.
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