Introduction: Migraine is a chronic neurological disease which has various etiological factors. It is important to highlight the importance of studies involving patients with migraine, as it generates significant limitations in quality of life. Objectives: To evaluate the association among pain impact, anthropometric status and others factors in migraine patients. Methods: Quantitative and descriptive, cross-sectional and secondary-based study, developed in a Clinical School of Pharmacy of the city of Salvador-BA, with patients treated with migraine diagnosis, from April 2018 to March 2019, of 20 years old or more. Information was gathered about demographic, socioeconomic, anthropometric, lifestyle, clinical, pain impact [by Migraine Disability Assessment (MIDAS) and Headache Impact Test-6 questionnaires (HIT-6)] and pain intensity (visual pain scale). Logistic regression models were used to evaluate the factors associated with the pain impact with a value of p≤0.05. Results: Of the 40 patients evaluated, 87.5% were female, the average age detected was 40.35 ± 12.6 years. There was a prevalence of sedentary (87.5%), overweight (55%), high waist circumference (68.4%), intestinal constipation (35%) and lactose intolerance (28.2%); high impact on daily activities: 62.5% (HIT-6) and 69.6% (MIDAS). Higher body mass index (BMI) and waist circumference (WC) averages were identified in patients with substantial/severe pain impact (p = 0.03 and p = 0.06, respectively) compared to those with no/some impact. The chances of greater impact of pain through HIT-6 seem to be associated with overweight (p = 0.04), female sex (p = 0.62) and physical inactivity (p = 0.89). Conclusion: Anthropometric status was associated with the impact of migraine. Overweight and female sex are related to migraine occurrence, and together with physical inactivity seem to influence the pain impact.
BACKGROUND AND OBJECTIVES:Considering the bidirectional connection between intestine and brain, the present study examined the association between migraine, lactose intolerance, and intestinal constipation in patients with status migrainosus. METHODS: This is a cross-sectional retrospective study that included 97 patients aged 20 years or older. The impact of pain was assessed by the Migraine Disability Assessment and the Headache Impact Test-6 questionnaires. The pain intensity was measured by the visual analog scale. Chi-square and Student-t tests were used for the statistical analysis. RESULTS:The sample consisted of 88.7% women, 56.8% overweight, 76.3% sedentary, 32% constipated and 23.7% lactose intolerant. Higher pain intensity (8.9±1.3) and impact pain mean was assessed by the Headache Impact Test-6 (67.6±5.3) and the Migraine Disability Assessment (36.7±26.3) in constipated patients compared to those without constipation. Lactose-intolerant patients presented higher migraine mean time (19.9±14.2) compared to lactose tolerant patients. Constipated and lactose intolerant patients presented higher prevalence of overweight (58.1 and 65.2%) and abdominal obesity (70.0 and 68.2%) compared to non-constipated and lactose tolerant patients, respectively. CONCLUSION: Although were observed in the evaluated sample a considerable prevalence of constipation and lactose intolerance, higher mean scores in the questionnaires used for pain impact and intensity in constipated patients and longer migraine diagnosis time in those with lactose-intolerance, there was no statistical significance in the association between migraine and these two gastrointestinal disorders.
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