Over 350 million people across the world suffer from major depressive disorder (MDD). More than 10% of MDD patients have suicide intent, while it has been reported that more than 40% patients did not consult their doctors for MDD. In order to increase consultation rate of potential MDD patients, we developed a novel MDD screening system which can be used at home without help of health-care professionals. Using a fingertip photoplethysmograph (PPG) sensor as a substitute of electrocardiograph (ECG), the system discriminates MDD patients from healthy subjects using autonomic nerve transient responses induced by a mental task (random number generation) via logistic regression analysis. The nine logistic regression variables are averages of heart rate (HR), high frequency (HF) component of heart rate variability (HRV), and the low frequency (LF)/HF ratio of HRV before, during, and after the mental task. We conducted a clinical test of the proposed system. Participants were 6 MDD patients (4 females and 2 males, aged 23–60 years) from Shizuoka Saiseikai General Hospital psychiatry outpatient unit and 14 healthy volunteers from University of Electro-Communications (6 females and 8 males, aged 21–63 years). The average PPG- and ECG (as a reference)-derived HR, HF and LF/HF were significantly correlated with each other (HR; r = 1.00, p < 0.0001, HF; r = 0.98, p < 0.0001, LF/HF; r = 0.98, p < 0.0001). Leave-one-out cross validation (LOOCV) revealed 83% sensitivity and 93% specificity. The proposed system appears promising for future MDD self-screening at home and are expected to encourage psychiatric visits for potential MDD patients.
One of the objectives of the performance measurement of grade-based higher education is to reduce the failure rate of students. To identify and reduce the number of failing students, the learning activities and behaviors of students in the classroom must be continuously monitored; however, monitoring a large number of students is an extremely difficult task. A penetration of web-based learning systems in academic institutions revealed the possibility of evaluating student activities via these systems. In this paper, we propose an early prediction scheme to identify students at risk of failing in a blended learning course. We employ a neural network on the set of prediction variables extracted from the online learning activities of students in a learning management system. The experiments were based on data from 1110 student who attended a compulsory, sophomore-level course. The results indicate that a neural-network-based approach can achieve early identification of students that are likely to fail; 25% of the failing students were correctly identified after the first quiz submission. After the mid-term examination, 65% of the failing students were correctly predicted.
BackgroundTo increase the consultation rate of potential major depressive disorder (MDD) patients, we developed a contact-type fingertip photoplethysmography-based MDD screening system. With the outbreak of SARS-CoV-2, we developed an alternative to contact-type fingertip photoplethysmography: a novel web camera-based contact-free MDD screening system (WCF-MSS) for non-contact measurement of autonomic transient responses induced by a mental task.MethodsThe WCF-MSS measures time-series interbeat intervals (IBI) by monitoring color tone changes in the facial region of interest induced by arterial pulsation using a web camera (1920 × 1080 pixels, 30 frames/s). Artifacts caused by body movements and head shakes are reduced. The WCF-MSS evaluates autonomic nervous activation from time-series IBI by calculating LF (0.04–0.15 Hz) components of heart rate variability (HRV) corresponding to sympathetic and parasympathetic nervous activity and HF (0.15–0.4 Hz) components equivalent to parasympathetic activities. The clinical test procedure comprises a pre-rest period (Pre-R; 140 s), mental task period (MT; 100 s), and post-rest period (Post-R; 120 s). The WCF-MSS uses logistic regression analysis to discriminate MDD patients from healthy volunteers via an optimal combination of four explanatory variables determined by a minimum redundancy maximum relevance algorithm: HF during MT (HFMT), the percentage change of LF from pre-rest to MT (%ΔLF(Pre–R⇒MT)), the percentage change of HF from pre-rest to MT (%ΔHF(Pre–R⇒MT)), and the percentage change of HF from MT to post-rest (%ΔHF(MT⇒Post–R)). To clinically test the WCF-MSS, 26 MDD patients (16 males and 10 females, 20–58 years) were recruited from BESLI Clinic in Tokyo, and 27 healthy volunteers (15 males and 12 females, 18–60 years) were recruited from Tokyo Metropolitan University and RICOH Company, Ltd. Electrocardiography was used to calculate HRV variables as references.ResultThe WCF-MSS achieved 73% sensitivity and 85% specificity on 5-fold cross-validation. IBI correlated significantly with IBI from reference electrocardiography (r = 0.97, p < 0.0001). Logit scores and subjective self-rating depression scale scores correlated significantly (r = 0.43, p < 0.05).ConclusionThe WCF-MSS seems a promising contact-free MDD screening apparatus. This method enables web camera built-in smartphones to be used as MDD screening systems.
E-learning can be a potential solution to educational inequality problem in developing countries, like Mongolia, with vast land and sparse population. With the introduction of Massive Open Online Courses (MOOCs), some impressive cases bring the attention of the public towards it. But there is no specific evidence that shows Mongolian students' experiences related to these online courses yet. Purpose of this study was to examine Mongolian students' MOOC perception and experience, especially influence of access, skills, and preferences in their practice. We used a 15-item questionnaire and results were based on 6846 students' responses. The study population consists of undergraduate students of the National University of Mongolia and high school students from 8 schools in Ulaanbaatar city. There was a significant difference between university and high school students in the awareness and enrollment rates. 47% of the students have heard of MOOCs and 2518 respondents (37%) had an experience of taking MOOCs. Our results show that students have a doubt about MOOC's academical quality and consider it as an additional source of learning materials. The results of this study can be used to compare students' perception from other developing countries.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.