DNA origami nanostructures are used to arrange gold nanoparticles into dimers with defined distance, which can be exploited as novel substrates for surface enhanced Raman scattering (SERS). Single dye molecules (TAMRA and Cy3) can be placed into the SERS hot spots, with Raman enhancement up to 1010, which is sufficient to detect single molecules by Raman scattering.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.