Today, mobile application (App) is a new emerging mobile technology and has been widely used. This new mobile artifact not only overturns the traditional business model of mobile industry, but also creates new avenues of mobile market opportunities. Although mobile pay-per-use services have attracted increased attention in recent years, few studies have provided limited insight into mobile technology adoption in pay-per-use services. In this study, we examine the determinants of behavioral intention of Apps users based on the theory of consumption values, and explore the roles of these values in mobile Apps context. Hypothesis testing was performed with structural equation modeling (SEM) on data collected from 282 mobile Apps users. The results reveal that consumption values significantly affect consumer behavioral intention to use mobile Apps. Among them, epistemic and motional values have stronger relationships with behavioral intention. Moreover, conditional value influences mobile App users' behavioral intention via the mediation of other consumption values (functional, social, emotional, and epistemic value). Finally, implications of the findings and areas for future research are discussed.

The directionally opposite changes in REM suggest that stressor controllability is an important factor in the effects of stress and stressful memories on sleep.

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Lengthy use of general anesthetics (GAs) causes neurobehavioral deficits in the developing brain, which has raised significant clinical concerns such that the United States Food and Drug Administration (FDA) is warning on the use of GAs in children younger than 3 years. However, the molecular and cellular mechanisms for GAs-induced neurotoxicity remain largely unknown. Here, we report that sevoflurane (Sevo), a commonly used GA in pediatrics, caused compromised astrocyte morphogenesis spatiotemporally correlated to synaptic overgrowth, with reduced synaptic function in developing cortex in a regional-, exposure-length-, and age-specific manner. Sevo disrupted astrocyte Ca 2+ homeostasis both acutely and chronically, which led to the down-regulation of Ezrin, an actin-binding membrane-bound protein, which we found was critically involved in astrocyte morphogenesis in vivo. Importantly, overexpression of astrocyte Ezrin rescued astrocytic and neuronal dysfunctions and fully corrected deficits in social behaviors in developing mice with lengthy Sevo exposure. Our data uncover that, in addition to neurons, astrocytes may represent important targets for GAs to exert toxic effects and that astrocyte morphological integrity is crucial for synaptogenesis and neurological behaviors.