Phellinus linteus biomass powder obtained after submerge-fermentation was assested for semi-chronic toxicity in rabbit for evaluation of the safety of using it as functional food. Rabbits were drunk test solution continuously in 28 days with 2 doses: 0.558 g/kg rabbit/ day and 2.792 g/kg rabbit/day. The result showed that the tested samples did not affect to weight, status, activity of tested rabbit. The biochemical index which expressed the liver, kidney functions had no statistical different at before test, after 14 days of test, after 28 days of test, and after 14 days finish of test between tested group and control group (without drink tested sample). The similarity results was obtained with hematological index. There were no abnormal occur in heart, liver, kidney, lung, spleen, and digestive system of tested rabbits in general observation as well as no histopathological lesions of the liver and kidneys in microscopic observation of tested group.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.