Purpose: To compare clinical outcomes in a prospective trial of cataract surgery patients bilaterally implanted with two different trifocal intraocular lenses (IOLs) with very similar optical designs but consisting of different IOL materials (hydrophobic and hydrophilic). Patients and Methods: Fifty-one patients (102 eyes) were randomized to receive trifocal IOLs bilaterally-FineVision POD F (hydrophilic) or FineVision POD F GF (hydrophobic) (both PhysIOL, Liége, Belgium). The follow-up period was 3 months. Outcome measurements included uncorrected distance (UDVA), corrected distance (CDVA), distance-corrected intermediate (DCIVA), and distance-corrected near visual acuity (DCNVA), refraction, negative dysphotopsia, optical quality of vision, contrast sensitivity under photopic and mesopic conditions, halometry (discrimination index), and patient-reported outcomes. Results: At the final study visit, mean (SD) values for binocular UDVA, CDVA, DCIVA (80 cm), and DCNVA (40 cm) were −0.01 (0.06), −0.04 (0.04), 0.09 (0.10), and 0.10 (0.09) logMAR, respectively, for POD F, and 0.01 (0.08), −0.03 (0.03), 0.08 (0.1), and 0.13 (0.11) respectively, for POD F GF. Defocus assessments showed a continuous curve with a functional range of visual acuity (≤0.15 logMAR) from ~30 cm to infinity in both groups. The discrimination index was >0.85 for all patients, and both groups showed similar contrast sensitivity under photopic and mesopic conditions. At 3 months, no patient reported negative dysphotopsia, and high satisfaction rates were observed. Conclusion: Clinical outcomes showed no significant difference between each lens when measured at 1 month and 3 months after implantation. This equally good clinical performance of hydrophilic and hydrophobic trifocal lenses allows the surgeon to choose the IOL material based on personal preferences or patients' needs.
Fabry disease is a rare X-linked disorder caused by an alpha-galactosidase enzyme deficiency, which leads to a progressive lysosomal glycosphingolipids accumulation, mainly globotriaosylceramide, in multiple organism tissues including the eye.This case series describes the first ophthalmological Colombian report of Fabry disease highlighting the importance of ocular signs as markers of the disease, useful in diagnosis and treatment to avoid long-term complications that lead to a morbi-mortality increment.We describe five cases of Fabry disease from Bogotá, Colombia, including a complete clinical history, ophthalmologic, optometric examination, and photographs. We found that all patients had refractive defects and that in all cases corneal verticillata pattern was found. Four patients presented with posterior capsule lens brown-beige deposits and four patients had conjunctival and retinal tortuous vessels. A complete ophthalmologic examination is important for prompt diagnosis, which is key to starting a multidisciplinary treatment and reducing morbi-mortality.
Purpose: To assess the difference in visual acuity and optical quality between two monofocal intraocular lens (IOL) models Material and Methods: Prospective, parallel and randomized clinical study. Sixty patients were implanted bilaterally, 30 per group, with IOL TECNIS® ZCB00 or Clareon® CNA0T0. Visual outcomes obtained at 1 and 3 months after surgery included both uncorrected and corrected monocular distance visual acuity (UCVA and DCVA, respectively), objective index scattering (OSI), modulation transfer function cutoff(MTF), Strehl Ratio (SR), contrast sensitivity (CS) defocus curve, IOL's spherical aberration (SA), and eye's longitudinal chromatic aberration (LCA). Patient's satisfaction was assessed using CatQuest-9SF questionnaire at 3 months postoperatively. Results: Regarding all the parameters assessed, there were statistically significant differences for DCVA (p = .008), OSI (p= .050) and SR (p= .003) between groups. Outcomes related to CS defocus curve showed statistically significant differences for vergences between -0.50 D and +1.00 D (3 mm pupil) and for vergences of 0.00 D and +0,50 D (4.5 mm pupil) between groups. Overall, IOL TECNIS® showed better results regarding visual acuity and optical quality, including a lower LCA result in comparison to Clareon®. Patient's satisfaction evaluated with CatQuest-9SF showed that TECNIS group achieved better outcomes although the differences were statistically significant only for the 'Reading text on television' item (p = 0.027). Conclusion: Both IOL models showed excellent quantity of vision, optical and visual quality as well as high patient's satisfaction after cataract surgery. Despite it, the TECNIS® ZCB00 model did provide slightly better outcomes, yet statistically significant, than the Clareon® CNA0T0
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