The diuretic activity of bumetanide has been studied in 16 Glasgow, London, and Sheffield, England Department of Medicine, Western Infirmary, Glasgow, Department of Therapeutics, Westminister Hospital, London, and Department of Pharmacology and Therapeutics, Royal Infirmary, Sheffield Bumetanide (3-n-butylamino-4-phenoxy-5-sulfamoylbenzoic acid, Brinex) is a derivative of metanilamide that displays potent diuretic activity on oral administration

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