We have obtained the first confocal microscopic sum frequency (SF) intensity images, using ZnS polycrystals as a sample. We have found different contrasts in the SF intensity images when the incident beams were focused at different depths in the ZnS sample. (© 2009 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)

This paper aims to demonstrate the efficacy of the immobilisation of the chemotherapy drug doxorubicin on nanodiamond platforms as a potential cancer therapy. This effective drug is experimentally fed into a human breast adenocarcinoma cell lines. Drug loading activity and cell viability are detected by spectrometer, microscopy, and MTT assay in this study at . Experimental results show that in the basic environment (pH ¼ 8.0), the nanodiamond carboxylic group cooperated with the doxorubicin amino group to form a stable and non-covalent bond on nanodiamond surfaces served as a simple physical adsorption. In an acidic environment suitable to targeting the cancer cells, the nanodiamond carboxylic group ionised so that doxorubicin is effectively released. Doxorubicin therefore affirmatively absorbed into the cytoplasm and later into the nucleus. The significant finding of the study is that IC-50 equivalent to 0.40 mg/mL and viable nanodiamond-doxorubicin is a good candidate material for drug delivery. ARTICLE HISTORY

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We report on the experimental observation of surface plasmon resonance in Cu nanowires fabricated by shadow deposition method. When the incident light is polarized perpendicular to the wire axes, plasmon maxima appeared at about 2.3 eV in the absorption spectra. Plasmon resonance appeared at lower photon energy when the incident light is polarized parallel to the wire axes. Resonance peaks move to lower energy when the nanowire widths are increased. We have found that finite-difference time-domain (FDTD) simulation gives better results than Maxwell-Garnett model in explaining the relation between the light polarization and the energies of the observed absorption maxima. r