Direct measurement of atp in seawater and application of ATP to monitor bacterial growth potential in SWRO pre-treatment systems. Desalination and Water Treatment, 99, 91-101.
Intel, Hillsboro, ORThe recent emphasis on power efficiency in serial I/O [1-4] reflects the growing need for lower-power chip-to-chip interfaces for computing systems. Boardlevel transceivers using a variety of low-power circuit techniques have demonstrated power efficiencies as low as 2.2mW/(Gb/s) across four data lanes [1]. Because power efficiency generally degrades as the per-lane data rate increases [2], low-power interfaces with high aggregate bandwidths must combine many parallel data lanes within the silicon, package and board area constraints. Parallel links can also reduce average power by disabling some or all lanes during periods of sub-peak bandwidth demand, but the efficiency and latency of this scheme is limited by wake-up time [4]. This paper describes a 470Gb/s binary NRZ parallel interface in 45nm CMOS that consumes 1.4mW/Gb/s. The circuitry and interconnect were co-designed to minimize power and area. Power is reduced by sharing clocking within "bundles" of data lanes, minimizing the span of clock signals and pairing a low-swing TX driver with a sensitive RX sampler. Silicon area is minimized by using on-chip transmission lines (TLs) to redistribute clock and data signals, while a dense, top-side package connector enables intra-bundle delay matching. The interface also has fast (<5ns) RX standby wake-up and an integrated wake-up time measurement circuit to enable aggressive power management. The interface and channel topology are intended for CPU-to-CPU and CPU-to-memory communication.Figure 8.1.1 shows the interconnect topology and link schematic. The link is asymmetric full-duplex with 19 lanes in one direction and 28 lanes in the opposite direction. The data lanes are organized into groups of 9 or 10, which are referred to as bundles. A single forwarded clock transmitter and injection-locked VCO (IL-VCO) are shared for each die. The interconnect topology consists of two packaged dies connected to a bridge board through top-side package connectors. This topology is compatible with either a high-density interconnect (HDI) or Flex cable, but the HDI implementation is the focus of this work. The data signals for each bundle are routed on a single layer of the bridge, and all lanes within a bundle are length matched to <100µm. This allows clock recovery to be done on a per-bundle basis. The package-to-bridge connector is a 500µm pitch LGA, which provides approximately 4X area density advantage over socket-to-PCB routing and facilitates length matching in the package breakout. The channel is continued on-die with length matched TLs that route the data and clock signals to centrally located TX and RX bundle circuitry ( Fig. 8.1.7). Each bundle occupies the area of only eight C4 bumps. The total area for active interface circuitry is 3.2mm 2 .Figure 8.1.2 shows the schematic for the TX portion of the interface. A supplyregulated IL-VCO generates the interface clock, emulating a system wherein multiple interfaces share a single PLL and filter the clock locally. Alternately, a per-interface PLL based...
In this study, the removal of particulate, organic and biological fouling potential was investigated in the two-stage dual media filtration (DMF) pretreatment of a full-scale seawater reverse osmosis (SWRO) desalination plant. Moreover, the removal of fouling potential in two-stage DMF (DMF pretreatment) was compared with the removal in two-stage DMF installed after dissolved air floatation (DAF) (DAF-DMF pretreatment). For this purpose, the silt density index (SDI), modified fouling index (MFI), bacterial growth potential (BGP), organic fractions and microbial adenosine triphosphate (ATP) were monitored in the pretreatment processes of two full-scale SWRO plants. Particulate fouling potential was well controlled through the two stages of DMF with significant removal of SDI15 (>80%), MFI0.45 (94%) and microbial ATP (>95%). However, lower removal of biological/organic fouling potential (24–41%) was observed due to frequent chlorination (weekly) of the pretreatment, resulting in low biological activity in the DMFs. Therefore, neutralizing chlorine before media filtration is advised, rather than after, as is the current practice in many full-scale SWRO plants. Comparing overall removal in the DAF-DMF pretreatment to that of the DMF pretreatment showed that DAF improved the removal of biological/organic fouling potential, in which the removal of BGP and biopolymers increased by 40% and 16%, respectively. Overall, monitoring ATP and BGP during the pretreatment processes, particularly in DMF, would be beneficial to enhance biological degradation and lower biofouling potential in SWRO feed water.
A multitude of samples is required to monitor and optimize the quality and reliability of quantitative measurements of (super-resolution) light microscopes. Here, we present a single sample to calibrate microscopes, align their laser beams and measure their point spread function (PSF) in 3D. The sample is composed of a refractive index matched colloidal crystal of silica beads with fluorescent and gold cores. The microscope can be calibrated in three dimensions using the periodicity of the crystal; the alignment of the laser beams can be checked using the reflection of the gold cores; and the PSF can be measured at multiple positions and depths using the fluorescent cores. It is demonstrated how this sample can be used to visualize and improve the quality of confocal and super-resolution images. The sample is adjustable to meet the requirements of different NA objectives and microscopy techniques and additionally can be used to evaluate refractive index mismatches as a function of depth quantitatively.
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