OBJECTIVETo determine whether breaking up prolonged sitting with short bouts of standing or walking improves postprandial markers of cardiometabolic health in women at high risk of type 2 diabetes. RESEARCH DESIGN AND METHODSTwenty-two overweight/obese, dysglycemic, postmenopausal women (mean 6 SD age 66.6 6 4.7 years) each participated in two of the following treatments: prolonged, unbroken sitting (7.5 h) or prolonged sitting broken up with either standing or walking at a self-perceived light intensity (for 5 min every 30 min). Both allocation and treatment order were randomized. The incremental area under the curves (iAUCs) for glucose, insulin, nonesterified fatty acids (NEFA), and triglycerides were calculated for each treatment condition (mean 6 SEM). The following day, all participants underwent the 7.5-h sitting protocol. RESULTSCompared with a prolonged bout of sitting (iAUC 5.3 6 0.8 mmol/L · h), both standing (3.5 6 0.8 mmol/L · h) and walking (3.8 6 0.7 mmol/L · h) significantly reduced the glucose iAUC (both P < 0.05). When compared with prolonged sitting (548.2 6 71.8 mU/L · h), insulin was also reduced for both activity conditions (standing, 437.2 6 73.5 mU/L · h; walking, 347.9 6 78.7 mU/L · h; both P < 0.05). Both standing (21.0 6 0.2 mmol/L · h) and walking (20.8 6 0.2 mmol/L · h) attenuated the suppression of NEFA compared with prolonged sitting (21.5 6 0.2 mmol/L · h) (both P < 0.05). There was no significant effect on triglyceride iAUC. The effects on glucose (standing and walking) and insulin (walking only) persisted into the following day. CONCLUSIONSBreaking up prolonged sitting with 5-min bouts of standing or walking at a selfperceived light intensity reduced postprandial glucose, insulin, and NEFA responses in women at high risk of type 2 diabetes. This simple, behavioral approach could inform future public health interventions aimed at improving the metabolic profile of postmenopausal, dysglycemic women.

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Complex training, a combination of resistance training and plyometrics is growing in popularity, despite limited support for its efficacy. In pre- and early pubertal children, the study of complex training has been limited, and to our knowledge an examination of its effect on anaerobic performance characteristics of the upper and lower body has not been undertaken. Furthermore, the effect of detraining after complex training requires clarification. The physical characteristics (mean+/-s) of the 54 male participants in the present study were as follows: age 12.3 +/- 0.3 years, height 1.57 +/- 0.07 m, body mass 50.3 +/- 11.0 kg. Participants were randomly assigned to an experimental (n = 33) or control group (n = 21). The training, which was performed three times a week for 12 weeks, included a combination of dynamic constant external resistance and plyometrics. After training, participants completed 12 weeks of detraining. At baseline, after training and after detraining, peak and mean anaerobic power, dynamic strength and athletic performance were assessed. Twenty-six participants completed the training and none reported any training-related injury. Complex training was associated with small increases (< or =5.5%) in peak and mean power during training, followed by decreases of a similar magnitude (< or = -5.9%) during detraining (P < 0.05). No changes or minor, progressive increases (< or =1.5%) were evident in the control group (P > 0.05). In the experimental group, dynamic strength was increased by 24.3 - 71.4% (dependent on muscle group; P < 0.01), whereas growth-related changes in the control group varied from 0 to 4.4% (P > 0.05). For 40-m sprint running, basketball chest pass and vertical jump test performance, the experimental group saw a small improvement (< or =4.0%) after training followed by a decline (< or = -4.4%) towards baseline during detraining (P < 0.05), whereas the control group experienced no change (P > 0.05). In conclusion, in pre- and early pubertal boys, upper and lower body complex training is a time-effective and safe training modality that confers small improvements in anaerobic power and jumping, throwing and sprinting performance, and marked improvements in dynamic strength. However, after detraining, the benefits of complex training are lost at similar rates to other training modalities.