The oxygen up-take of irradiated aqueous solutions of xanthene dyes has been investigated by means of Warburg’s apparatus, and evidence for a switch-over from a D–O to a D–D mechanism is obtained from the variation of dye-concentration. This view is supported by the photobleaching rate and the oxygen concentration effect at high eosine concentrations (∼10−4m).
The quautum yields (γo2) of the consumption are estimated and it is found that γo2(D–D) is larger than γo2(D–O).
Persistent atrial standstill is a very rare pathophysiologic condition whose diagnosis is established when both electrical and mechanical silence of the atria are confirmed. To test the hypothesis that secretion of atrial natriuretic peptide is disturbed in patients with persistent atrial standstill, the response of atrial natriuretic peptide secretion and other neurohormonal factors during exercise was investigated in three patients with a rate-responsive ventricular demand (VVI) pacemaker implanted for confirmed persistent atrial standstill. The results were compared with those observed in eight normal subjects and patients with a rate-responsive VVI (Group A) or atrial demand (AAI) (Group B) pacemaker implanted for confirmed sick sinus syndrome. Patients in Group A displayed significant elevation of alpha-human atrial natriuretic peptide secretion both before and during exercise (122.5 +/- 14.8 and 207.5 +/- 8.3 pg/ml, respectively) compared with those in Group B (55 +/- 14.1 and 116.4 +/- 51.5 pg/ml, respectively) and the normal subjects (18.9 +/- 9.8 and 30.8 +/- 19.2 pg/ml, respectively). This indicated development of a nonphysiologic increase in atrial volume or pressure overload, or both, in rate-responsive VVI pacing because of lack of atrioventricular synchrony. However, patients with persistent atrial standstill had undetectable (less than 10 pg/ml) or almost undetectable secretion of atrial natriuretic peptide as well as lower levels of cyclic guanosine monophosphate in the circulation both before and during exercise. Changes in plasma catecholamines during exercise were similar in patients with persistent atrial standstill compared with the other groups. This study indicates that "endocrinologic silence" accompanies electrical and mechanical silence of the atria, which may constitute a third diagnostic clue to persistent atrial standstill.
Brain metastases from endometrial carcinomas are rare and the treatment is usually difficult. Here, we report a patient with stage IV endometrial carcinoma whose brain metastases showed complete remission after stereotactic radiosurgery using a gamma-knife. A 48-year-old woman underwent removal of a single brain metastatic lesion, and one month later underwent hysterectomy for endometrioid-type G3, endometrial adenocarcinoma. After hysterectomy, a cranial magnetic resonance imaging (MRI) demonstrated multiple brain metastases and the patient received two courses of stereotactic radiosurgery and six courses of chemotherapy. Complete response of the brain lesions was obtained, and she is well without recurrence 38 months after the second stereotactic radiosurgery.
A large quantity of dimethyl sulfoxide (DMSO) wastewater is discharged from washing and rinsing processes in semiconductor manufacturing industry. Traditional biological treatment is known to be difficult for the treatment of DMSO-containing wastewater because of odor problems. Ozonation of DMSO combined with a biological process is suggested to be a cost-efficient treatment solution, whereas the application of ozone to wastewater treatment has been limited by its low utilization efficiency and high cost. In this study, we applied an ozone microbubble generator to increase ozone transfer efficiency in the aqueous solution. The oxidation of DMSO by ozone microbubbles was investigated in a bubble column reactor with an inner diameter of 20 cm. We studied the dependence of DMSO degradation on the gas and liquid flow rates. Experimental results indicate that the ozonation of DMSO is a first-order mass-transfer-controlled reaction and the reaction rate constant increases with increasing gas velocity. Ozone transfer ratio increases with decrease in gas flow rate.
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