Introduction: Motor vehicle accident is a major problem in Malaysia. The statistics shows an increasing number of accidents (year 1997 to 2007). Fatigue and drowsiness among the drivers has been identified as one of the main reasons behind fatal crashes and injuries especially driving in long and monotonous motorway. This study aims to determine the driver's driving performance and physiological change of EEG in association with external factors such as driving condition and environmental background factors in a prolonged simulation study. Result: The study showed that time-on-task effect had significantly deteriorated drivers' alertness and impaired driving performance in an extended driving period, when certain driving condition and environmental factors considered. Conclusion: This study shows that prolong driving had significantly induced drivers' fatigue level exclusively with monotonous environment. Extended driving period deteriorated drivers' performance, revealing that time-on-task effect could possibly put drivers on a higher risk to be involved in traffic accident.
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