ObjectiveTo investigate the role of quantitative analysis of T2 relaxation time in the magnetic resonance imaging (MRI) diagnosis of breast cancer.MethodsThe study enrolled patients with clinical breast masses who were examined using MRI at eight different echo times. The differences in T2 relaxation time of benign and malignant breast lesions were analysed.ResultsA total of 67 patients (67 breast lesions: 46 malignant, 21 benign) were examined. The mean ± SD T2 relaxation time was significantly lower in the 46 malignant lesions compared with the 21 benign lesions (82.69 ± 15.37 ms versus 95.48 ± 26.51 ms, respectively). The area under the curve was 0.731. Using 79.52 ms as the cut-off between benign and malignant breast lesions, a sensitivity of 85.7% and a specificity of 58.7% were obtained.ConclusionsThere was a significant difference in T2 relaxation time between benign and malignant breast lesions. The specificity of using T2 relaxation time alone for the differentiation of benign from malignant lesions was not high, but it could constitute a new adjunct in the MRI diagnosis of breast cancer.
A 29-year-old Chinese man with good past health presented in October 2018 with acute abdominal pain and distension. On admission, he was afebrile and normotensive (blood pressure 116/79, pulse 74). Physical examination revealed a grossly distended abdomen with sluggish bowel sounds and mild diffuse tenderness but no guarding or rigidity. Preliminary blood tests showed leucocytosis (17.7 × 10 9 /L) and metabolic acidosis (pH 7.29, base excess-4.3). Markedly dilated large bowel loops were seen on radiograph. A flexible sigmoidoscopy performed to exclude sigmoid volvulus revealed no twisting point but was incomplete due to the presence of large amounts of stool. Urgent contrast computed tomography abdomen and pelvis showed that the entire length of the colon was grossly dilated up to 13 cm in diameter with loss of haustration and no obstructive mass, suggestive of megacolon. Several segments showed diminished mural enhancement. Bilateral avidly enhancing heterogeneous adrenal
Paratesticular mesothelioma is a rare differential diagnosis in the presence of scrotal hydrocele. A 17-year-old boy presented with a 3-year history of progressive hydrocele. Sonography revealed a large left paratesticular mass within the hydrocele. Serum tumor markers were negative. Left hydrocelectomy was performed and pathological analysis of the epididymal mass revealed a well-differentiated papillary mesothelioma. We discuss the sonographic and pathological findings of this rare neoplasm.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.