Aspergillus flavus is the second-most common Aspergillus species isolated from human infection and the second leading cause of invasive and non-invasive aspergillosis in tropical countries, predominantly in Asia, the Middle East and Africa. 1 The treatment of aspergillosis typically involves a primary therapy with triazole antifungals. 2 Additionally, triazoles are an important group of successful fungicides used for more than 40 years to control fungal phytopathogens in agriculture owed to their effectiveness in a broad range of fungi. 3 These antifungals target fungal 14-α sterol demethylases (CYP51s), key enzymes in the biosynthetic
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