Return to daily life Early mobilization program Comprehensive CR (disease management program) Discharge from hospital, Return to home Maintain comfortable life, Prevention of recurrence Returning to society-workforce, Establish new healthy lifestyle Inpatient rehabilitation program (CCU/ICU/ward) *Notation of corporation is omitted.

OBJECTIVE -To detect whether mild exercise training improves glucose effectiveness (S G ), which is the ability of hyperglycemia to promote glucose disposal at basal insulin, in healthy men.RESEARCH DESIGN AND METHODS -Eight healthy men (18 -25 years of age) underwent ergometer training at lactate threshold (LT) intensity for 60 min/day for 5 days/week for 6 weeks. An insulin-modified intravenous glucose tolerance test was performed before as well as at 16 h and 1 week after the last training session. S G and insulin sensitivity (S I ) were estimated using a minimal-model approach.RESULTS -After the exercise training, VO 2max and VO 2 at LT increased by 5 and 34%, respectively (P Ͻ 0.05). The mild exercise training improves S G measured 16 h after the last training session, from 0.018 Ϯ 0.002 to 0.024 Ϯ 0.001 min Ϫ1 (P Ͻ 0.05). The elevated S G after exercise training tends to be maintained regardless of detraining for 1 week (0.023 Ϯ 0.002 min Ϫ1 , P ϭ 0.09). S I measured at 16 h after the last training session significantly increased (pre-exercise training, 13.9 Ϯ 2.2; 16 h, 18.3 Ϯ 2.4, ϫ10 Ϫ5 ⅐ min Ϫ1 ⅐ pmol/l -1 , P Ͻ 0.05) and still remained elevated 1 week after stopping the training regimen (18.6 Ϯ 2.2, ϫ10 Ϫ5 ⅐ minCONCLUSIONS -Mild exercise training at LT improves S G in healthy men with no change in the body composition. Improving not only S I but also S G through mild exercise training is thus considered to be an effective method for preventing glucose intolerance.

RBF showed no significant decrease until 80% LaBP, and decreased with an increase in blood lactate. Reduction in RBF with exercise above the intensity at LaBP was due to decreased cross-sectional area rather than time-averaged flow velocity.

The associations between the presence or severity of coronary artery disease (CAD) and measurements of various kinds of fat as assessed by multidetector row computed tomography (MDCT) are unclear. We enrolled 300 patients who were clinically suspected to have CAD or who had at least one cardiac risk factor and had undergone MDCT. The number of significantly stenosed coronary vessels (VD), and measurements of pericardial fat index, paracardial fat index, epicardial fat index, visceral fat index, and subcutaneous fat index were quantified using MDCT. Plasma levels of adiponectin, pentaxin-3, and high-sensitivity C-reactive protein factors were also measured. Pericardial fat index, paracardial fat index, and visceral fat index in a CAD group were significantly greater than those in a non-CAD group. In addition, the levels of these fat indices tended to increase as the number of VD increased and were positively correlated with the Gensini score. The area-under-the-curve for paracardial fat index was significantly greater than those for the other parameters of fat index measured by a receiver-operating characteristic curve analysis. The cut-off level of paracardial fat index that gave the greatest sensitivity and specificity for the diagnosis of CAD was 54.9 cm/m (sensitivity 0.710, specificity 0.552). The presence of CAD was independently associated with paracardial fat index, in addition to age and diabetes mellitus, by a multiple logistic regression analysis. In conclusion, paracardial fat index may be a marker for evaluating the presence or severity of CAD.