Two biologically active compounds were synthesized and their crystal structures were determined. The characteristic feature of both structures is mol­ecular layers in the crystal lattice formed via C—H⋯O and O—H⋯O inter­actions. The mol­ecular Hirshfeld surfaces analysis were explored with two-dimensional fingerprint plots for the title compounds and other known structures from the literature. Additionally, the lipophilicity parameters (logP) were determined and related to the C⋯H contact contribution in the Hirshfeld surface.