A prospective study was conducted in slum children to determine the incidence of post-measles corneal disease and to clarify its relationship with nutritional status. A total of 318 cases of measles were identified over a period of 15 mo; maximum incidence was observed for children between 1-2 yr. Most of the children showed weight loss and serum proteins decrease during the acute stage of measles. Corneal lesions were observed in 3% of the children, and the lesions responded well to treatment. Serum vitamin A and RBP levels were significantly depressed during the acute stage of measles but were restored to normal 8 wk after recovery. There were no significant differences in the serum levels for those with and without eye lesions, which suggests that these lesions may not be mediated simply through the effect of infection on serum concentration of vitamin A.
Fermentation technology plays a very important role in the field of Biotechnology. Production of various enzymes, antibiotics, single cell proteins, various food products, etc is carried out in a vessel called as the bioreactor which is the seed of fermentation technology. The project includes study of Pectinase production using submerged fermentation and various parameters like different substrate, different strains and fermentation time to obtain the maximum yield of Pectinase. To achieve this various research is being conducted. Aspergillus Niger species was being used in this work for the production of Pectinase.
Lactam and Amide Acetals. Part 21. Use of Pyroglutamic Acid and Proline in Chiral Synthesis of Conformationally Constrained Piperazinones.-Semirigid bicyclic piperazinones are conveniently synthesized starting from chiral pyroglutamates (cf. (IV)) or prolines (cf. (VII)/(VIII)). Key step in the similar sequences is a stereoselective catalytic hydrogenation of the corresponding, readily available nitroenamines, which results in a spontaneous cyclization. -(JAIN, S.; SUJATHA, K.; KRISHNA, K. V. R.; ROY, R.; SINGH, J.; ANAND, N.; Tetrahedron 48 (1992) 23, 4985-4998; Med. Chem.
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