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Chemical warfare agents (CWAs) have been listed as lethal weapons of mass destruction due to their extreme toxicity and devastating effects. Detection and detoxification are essential to protect ourselves from such acutely perilous agents and have therefore generated a great deal of research interest. In this context, studies show that adsorbents such as activated carbon, metal oxides, and metal organic frameworks (MOFs) are active materials for the effective degradation of CWAs. Among them, MOFs are preferred because of their large surface area, tunable porosity, and catalytic, functional, and chemical stability properties. With this background, we comprehensively review the historical purview of the utility of CWAs, the potency of various CWAs, and their toxic profiles. Further, we discuss the research strategies reported to synthesize MOFs of desirable characteristics by tuning the synthesis parameters such as solvents, temperature, guest molecules, and organic ligands. Specifically, we highlight the multifarious studies of the impregnation of MOFs onto fibers/textiles as selfprotecting fabrics using different techniques. Finally, we enumerate the challenges in developing MOFs-incorporated textiles and their functionalization toward the detection and detoxification of CWAs. As a future perspective, further requirements and possibilities of using MOF-modified textiles as wearable electronic devices for the detection and detoxification of CWAs have also been addressed.

We report the fabrication of a breath sensor using nanostructured Co3O4 thin films for the detection of acetone in exhaled breath, which is one of the prominent bio-markers of Diabetic Ketoacidosis (DKA).