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Predictions of surface water exposure to "down-the-drain" chemicals are presented which employ grid-based spatially-referenced data on average monthly runoff, population density, country-specific per capita domestic water and substance use rates and sewage treatment provision. Water and chemical load are routed through the landscape using flow directions derived from digital elevation data, accounting for in-stream chemical losses using simple first order kinetics. Although the spatial and temporal resolution of the model are relatively coarse, the model still has advantages over spatially inexplicit "unit-world" approaches, which apply arbitrary dilution factors, in terms of predicting the location of exposure hotspots and the statistical distribution of concentrations. The latter can be employed in probabilistic risk assessments. Here the model was applied to predict surface water exposure to "downthe-drain" chemicals in China for different levels of sewage treatment provision.Predicted spatial patterns of concentration were consistent with observed water quality classes for China.Key Words: Global, Exposure, Chemical, Model, China Capsule AbstractA global-scale model was used to predict spatial patterns of "down-the-drain" chemical concentrations in China. Predictions were consistent with observed water quality classes, demonstrating the potential value of the model.3

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