Aim To study effect of delmopinol hydrochloride (DEL) in comparison with chlorhexidine digluconate (CHX) and a placebo (PLA) in addition to non‐surgical mechanical debridement in patients with peri‐implant mucositis. Materials and methods Eighty‐nine patients with at least one implant diagnosed with peri‐implant mucositis were randomly assigned to one of three study groups (DEL, CHX and PLA). Professional non‐surgical mechanical debridement was performed at baseline. Mouth rinsing was carried out by the patients twice a day in addition to their regular oral hygiene practices. Assessments of efficacy were performed for the primary outcome ‐ Implant bleeding on probing (IBOP%) and secondary outcomes ‐ modified Bleeding Index (mBI) and modified Plaque Index (mPI) at 1 and 3 months. Results At 3 months, there was statistically significant reduction in IBOP% and mBI within the study groups compared to baseline. However, there was no statistically significant difference between the study groups at 3 months follow‐up. Moreover, there was a statistically significant difference according to mPI at 1 month between the chlorhexidine and placebo group (p = .004). Conclusions This study confirms that mechanical debridement combined with oral hygiene instruction is effective in treatment of peri‐implant mucositis. The clinical effects between groups were comparable.
(v , 0) Werner bands for v = 0-4, using a narrow-band tunable extreme UV laser source at wavelengths λ = 92-105 nm in conjunction with the technique of 1 + 1 two-photon ionization. The measurements can be divided into three categories for which varying absolute accuracies were obtained. Special focus was on the B, v = 2-5 bands, where an accuracy of 0.004 cm −1 or δν/ν = 4 × 10 −8 is achieved. For transitions to B, v ≤ 13 and C, v ≤ 3 states the accuracy is 0.005 cm −1 or δν/ν = 5 × 10 −8 . Due to a different frequency mixing scheme uncertainties for B, v ≥ 13 and C, v = 4 are at the level of 0.011 cm −1 or δν/ν = 1.1 × 10 −7 . Inspection of combination differences between R(J ) and P(J + 2) lines shows that the accuracies are even better than estimated in the error budget. Based on the measurements of 138 spectral lines and the known combination differences, transition frequencies of 60 P-lines could be calculated as well, so that a data base of 198 accurately calibrated lines results for the Lyman and Werner bands of H 2 .Key words: vacuum UV, molecular spectroscopy, hydrogen, precision metrology. . Un examen des différences des combinaisons entre les raies R(J ) et P(J + 2) montre que les précisions sont meilleures que celles évaluées dans le budget des erreurs. Sur la base de mesures de 138 raies spectrales et de différences de combinaison connues, on a pu aussi calculer les fréquences de transition de 60 raies P et il en résulte qu'une base de données de 198 raies bien calibrées est disponible pour les bandes de Lyman et de Werner du H 2 .
Aim: To assess the microbial effects of mechanical debridement in conjunction with a mouthrinse on sites with peri-implant mucositis and gingivitis.Materials and methods: Eighty-nine patients with peri-implant mucositis were included in a double-blinded, randomized, placebo-controlled trial with mechanical debridement and 1-month use of either delmopinol, chlorhexidine (CHX), or a placebo mouthrinse. Submucosal and subgingival plaque samples of implants and teeth were collected at baseline and after 1 and 3 months, processed for 16S V4 rRNA gene amplicon sequencing, and analysed bioinformatically. Results:The sites with peri-implant mucositis presented with a less diverse and less anaerobic microbiome. Exposure to delmopinol or CHX, but not to the placebo mouthrinse resulted in microbial changes after 1 month. The healthy sites around the teeth harboured a more diverse and more anaerobe-rich microbiome than the healthy sites around the implants.Conclusions: Peri-implant sites with mucositis harbour ecologically less complex and less anaerobic biofilms with lower biomass than patient-matched dental sites with gingivitis while eliciting an equal inflammatory response. Adjunctive antimicrobial therapy in addition to mechanical debridement does affect both dental and peri-implant biofilm composition in the short term, resulting in a less dysbiotic subgingival biofilm.
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