Hypothesis: Pancreaticogastrostomy is a safe operation for a variety of periampullary conditions. Design: Retrospective review of a prospectively collected database. Setting: An academic tertiary care university hospital and a Veterans Affairs hospital. Patients: A total of 235 consecutive patients who underwent pancreaticogastrostomy. Main Outcome Measures: Indications for surgery, preoperative risk factors, intraoperative and postoperative variables, and factors that affect postoperative complications. Results: The most common initial symptoms were jaundice (73.2%), weight loss (23.8%), and abdominal pain (17.0%). The 4 most common indications for surgery were pancreatic adenocarcinoma (41.3%), ampullary carci
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