This study examined the latent structure and validity of inattention, hyperactivity-impulsivity, and sluggish cognitive tempo (SCT) symptomatology. We evaluated mother and teacher ratings of ADHD and SCT symptoms in 140 Puerto Rican children (55.7% males), ages 6 to 11 years, via factor and regression analyses. A three-factor model (inattention, hyperactivity-impulsivity, and SCT) provided the best fit for both sets of ratings. Inattention was the strongest correlate of lower scores on neuropsychological, achievement, and psychosocial measures. Externalizing problems were most strongly associated with hyperactivity-impulsivity, and internalizing problems were most strongly associated with parent-rated SCT and teacher-rated Inattention. SCT was not associated with executive function but was negatively associated with math. Inattention accounted for a disproportionate amount of ADHD-related impairment, which may explain the restricted discriminant validity of DSM-IV types. The distinct factors of hyperactivity-impulsivity and SCT had unique associations with impairing comorbidities and are roughly equivalent in predicting external correlates of ADHD-related impairment.

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These findings suggested that parents perceive greater child-related impact and place greater burden from having a male child with hyperactivity. Inattention, hyperactivity, and oppositional defiant behaviors are associated with global parent-child interactive stress but the pattern of associations will vary depending upon the behavior, child gender, and context of family life examined.

Online partner-seeking applications are sexual-identity affirming social spaces commonly accessed by young men who have sex with men (YMSM; ages 18 -24 years). Yet, prior studies with YMSM have observed sexual discrimination based on race/ethnicity and physical appearance to be common within these platforms. Few studies have explored the associations between online discrimination when partner-seeking and mental health. Our study's objective was to describe the prevalence of online sexual discrimination and test its associations with self-esteem and depression. We included cross-sectional data from the baseline survey of a web-based, HIV-prevention prospective randomized controlled trial for single YMSM (N ϭ 172) who reported seeking partners online. A national sample was recruited online from popular social and sexual networking sites. Using multivariable linear regressions, we tested the respective associations that race-based and appearance-based sexual discrimination had with self-esteem and depressive symptoms. We conducted stratified models by race/ethnicity (White vs. minority participants) and BMI categories (under-/normal weight vs. overweight/obese). Over 30% were exposed to race-based sexual discrimination and over 60% to appearance-based sexual discrimination. Weight-based sexual discrimination was associated with lower self-esteem. This association remained statistically significant in stratified models for racial/ethnic minority and overweight/obese participants only. Weightbased discrimination was positively associated with depressive symptoms among racial/ethnic minority YMSM. Our study highlights the potential contribution of weight-based discrimination when seeking partners online on YMSM's mental health. Coupled with community-level interventions to raise awareness about weight-related stigma, partner-seeking platforms should capitalize on opportunities for mass-media marketing strategies to promote body-type diversity and body-positive messaging. Public Significance StatementYoung men who have sex with men report race-based and weight-based sexual discrimination when seeking partners online. Despite high prevalence in our sample, race-based discrimination was not associated with mental health. Weight-based discrimination was negatively associated with selfesteem and positively associated with depression. Queer-targeted mass-media interventions that capitalize on promoting body-type diversity may be integral to shifting community norms away from rigid standards of attractiveness and ultimately having a positive impact on individual-level mental health.

Multipurpose prevention technologies (MPT) have been increasingly researched for their dual-purpose preventative properties against HIV and other STIs. The acceptability of PC-1005, a topical MPT candidate, was explored among men and women participating in the MTN-037 Phase I trial at two U.S. sites (Pittsburgh, PA, and Birmingham, AL). We triangulated quantitative and qualitative assessments of the acceptability of three volumes (4 mL, 16 mL, 32 mL) of PC-1005 administered rectally (N = 12; 6 males, 6 females). Participants rated overall gel acceptability on a scale of 1–10, with a median of 7.17 (SD = 2.04) and had positive feelings about all three dose volumes, citing them to be very comfortable or comfortable (dose 1 = 91.7%; dose 2 = 91.7%; dose 3 = 83.3%). High acceptability of and comfort with all three dose volumes shows promise for PC-1005 as an MPT to prevent HIV and STIs, warranting future clinical development.