Health Education Systems Incorporated (HESI(™)) test results, course grades, and National Council Licensure Examination-Registered Nurse (NCLEX-RN(®)) outcomes of students in an associate degree nursing program at a midwestern public university were investigated. Statistical analysis revealed that introductory Fundamentals HESI test scores, more than either comprehensive HESI Exit Exam scores or other specialty HESI test scores, significantly predicted NCLEX-RN outcomes in this study (p < 0.05), while controlling for grade point average and high school percentile rank. In addition, of the general education courses and the nursing courses in the associate nursing program examined, Pediatric Nursing, Medical-Surgical Nursing, and Maternity Nursing course grades were found most statistically significantly influential of all the HESI test scores (p < 0.01).
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